Full title: Restriction enzymes : a history / Wil A.M. Loenen (Leiden University Medical Center).

Author/creator: Loenen, Wil A. M.

Call Numbers: G 2020/1870

Record Identifier: 74VKaDra3klg

Language: English

Formats: Books

Contents: xiv, 346 pages : illustrations (chiefly color) ; 24 cm, , , , Preface -- Abbreviations -- Introduction -- Discovery of a barrier to infection and host-controlled variation: 1952-1953 -- Host-controlled variation is methylation and restriction of DNA: the 1960s -- The discovery of type II restriction enzymes: the 1970s -- Expansion and cloning restriction enzymes: the 1970s and early 1980s -- The first decade after the discovery of EcoRI: biochemistry and sequence analysis during the 1970s and early 1980s -- Variety in mechanisms and structures of restriction enzymes: ~1982-1993 -- Crystal structures of type II restriction enzymes and discovery of the common core of the catalytic domain: ~1993-2004 -- Improved detection methods, single-molecule studies, and whole-genome analyses result in novel insights in structures, functions, and applications of type I, II, III, and IV restriction enzymes: ~2004-2016 -- Summary and conclusions -- Appendix A: The history of restriction enzymes October 19-21, 2013 meeting program -- Appendix B: Modern-day applications of restriction enzymes -- Index -- About the author.

Publishers: Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, [2019]

Notes: Includes bibliographical references and index.

Permalink: https://collection.sl.nsw.gov.au/record/74VKaDra3klg

DDC: 572.76

MMS ID: 991024298612002626