Full title: Metabolic regulation in mammals / David M. Gibson, Robert A. Harris.

Author/creator: Harris, Robert A. (Robert Allison), 1939-, Gibson, David M., 1923-.

Date: 2002..

Call Numbers: N572.419/1

Record Identifier: 74Vvb73qJ66d

Language: English

Formats: Books

Contents: xiv, 224 p. : ill. ; 25 cm., Introduction. 1.1. Evolution of synthetic systems. 1.2. Hierarchies of biomolecules. 1.3. Membranes of animal cells. 1.4. Coupled reactions. 1.5. Enzyme catalysis. 1.6. Steady-state turnover. 1.7. The animal organism -- Enzyme-catalyzed Reactions. 2.1. Energetics of chemical reactions. 2.2. Coenzymes. 2.3. Multienzyme pathways. 2.4. Catalysis. 2.5. Kinetics of enzyme-catalyzed reactions -- Regulatory Mechanisms. 3.1. Introduction: levels of control. 3.2. Cell-to-cell communication elicits specialized cellular responses. 3.3. The specific signal-response connection. 3.4. Intracellular signal transduction from receptors to target proteins. 3.5. Signal-response to beta-adrenergic hormones. 3.6. Glucagon signal pathway. 3.7. Insulin signal pathway. 3.8. Functional target proteins. 3.9. Additional signal transduction systems., 4. Nutrient Homeostasis. 4.1. Introduction. 4.2. Digestion and distribution of exogenous nutrients. 4.3. Flows of nutrients among tissues in well-fed and starvation states. 4.4. Quality of nutrients. 4.5. Metabolic demand. 4.6. Circadian clocks -- 5. The Red Blood Cell. 5.1. Cell structure. 5.2. Dissipative systems. 5.3. Cellular homeostasis . 5.4. Glycolysis. 5.5. Homeostasis of electrolytes. 5.6. Replacement synthesis of cellular components. 5.7. Maintenance of reductive status. 5.8. Support of cellular homeostasis by the organism. 5.9. Specialized function of the RBC -- 6. Muscle metabolism. g6.1. 6.2. Glycolysis, glycogenolysis and glycogenesis. 6.3. Oxidative decarboxylation of pyruvate. 6.4. The citric acid cycle. 6.5. Electron transport. 6.6. Oxidative phosphorylation., 6.7. Fatty acid oxidation . 6.8. Regulation of fuel selection in various metabolic states. 6.9. Mitochondria and oxygen toxicity -- 7. Adipose Tissue metabolism. 7.1. Introduction. 7.2. Synthesis of TG and fatty acids. 7.3. Control of metabolic flux. 7.4. Coordinate induction and repression of lipogenic enzymes. 7.5. Reversible phosphorylation. 7.6. Allosteric feedback. 7.7. Hormone-sensitive lipase. 7.8. Negative feedback by leptin: lipostatic control -- 8. Liver Metabolism. 8.1. 8.2. Regulation of liver metabolic processes in the well-fed state. 8.3. Regulation of liver metabolic processes in the starved state. 8.4. Urea synthesis and its control. 8.5. Cholesterol metabolism and its control.

Publishers: New York : Taylor & Francis, 2002.

Notes: Lifelines. Includes bibliographical references.

Permalink: https://collection.sl.nsw.gov.au/record/74Vvb73qJ66d

DDC: 572.419

MMS ID: 991014806479702626