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Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

Full title: Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

Author/creator: Liu, Wei, He, Youyou, Guo, Zhongjie, Wang, Miaomiao, Han, Xiaodong, Jia, Hairui, He, Jin, Miao, Shanshan, Wang, Shengzheng.

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Record Identifier: TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

Language: English

Formats: Articles

Publishers: England: Taylor & Francis

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

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    Record title

    Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

    Record identifier

    TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

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    Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

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    https://collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

    Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

    Full title

    Discovery of potent tubulin inhibitors targeting the colchicine binding site via structure-based lead optimization and antitumor evaluation

    Author / Creator

    Liu, Wei ; He, Youyou ; Guo, Zhongjie ; Wang, Miaomiao ; Han, Xiaodong ; Jia, Hairui ; He, Jin ; Miao, Shanshan ; Wang, Shengzheng

    Publisher

    England: Taylor & Francis

    Journal title

    Journal of enzyme inhibition and medicinal chemistry, 2023, Vol.38 (1), p.2155815-2155815

    Record Identifier

    TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

    Language

    English

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    Articles

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    Animals Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology antitumour activity Binding Sites Cell Line, Tumor Cell Proliferation Colchicine - chemistry colchicine binding site Drug Screening Assays, Antitumor Humans Molecular Structure Research Paper structural optimisation Structure-Activity Relationship Tubulin - metabolism Tubulin inhibitors Tubulin Modulators - chemistry Tubulin Modulators - pharmacology

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    Record Identifier

    TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_crossref_primary_10_1080_14756366_2022_2155815

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