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Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

Full title: Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

Author/creator: De Biasi, Sara, Meschiari, Marianna, Gibellini, Lara, Bellinazzi, Caterina, Borella, Rebecca, Fidanza, Lucia, Gozzi, Licia, Iannone, Anna, Lo Tartaro, Domenico, Mattioli, Marco, Paolini, Annamaria, Menozzi, Marianna, Milić, Jovana, Franceschi, Giacomo, Fantini, Riccardo, Tonelli, Roberto, Sita, Marco, Sarti, Mario, Trenti, Tommaso, Brugioni, Lucio, Cicchetti, Luca, Facchinetti, Fabio, Pietrangelo, Antonello, Clini, Enrico, Girardis, Massimo, Guaraldi, Giovanni, Mussini, Cristina, Cossarizza, Andrea.

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Record Identifier: TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

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    Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

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    TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

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    Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

    Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

    Full title

    Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

    Author / Creator

    De Biasi, Sara ; Meschiari, Marianna ; Gibellini, Lara ; Bellinazzi, Caterina ; Borella, Rebecca ; Fidanza, Lucia ; Gozzi, Licia ; Iannone, Anna ; Lo Tartaro, Domenico ; Mattioli, Marco ; Paolini, Annamaria ; Menozzi, Marianna ; Milić, Jovana ; Franceschi, Giacomo ; Fantini, Riccardo ; Tonelli, Roberto ; Sita, Marco ; Sarti, Mario ; Trenti, Tommaso ; Brugioni, Lucio ; Cicchetti, Luca ; Facchinetti, Fabio ; Pietrangelo, Antonello ; Clini, Enrico ; Girardis, Massimo ; Guaraldi, Giovanni ; Mussini, Cristina ; Cossarizza, Andrea

    Publisher

    England: Nature Publishing Group

    Journal title

    Nature communications, 2020, Vol.11 (1), p.3434-3434

    Record Identifier

    TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

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    English

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    Adult Aged Aged, 80 and over Betacoronavirus - immunology Biomarkers - metabolism CD4 antigen CD4-positive T cells CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism CD4-Positive T-Lymphocytes - pathology CD57 antigen CD8 antigen CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - pathology Cell activation Cell differentiation Cellular Senescence Chemokine receptors Coronavirus Infections - blood Coronavirus Infections - immunology Coronavirus Infections - pathology Coronaviruses COVID-19 Cytokine Release Syndrome Cytokines Cytokines - immunology Cytokines - metabolism Exhaustion Female Flow cytometry Health care Health risks Helper cells Humans Immune system Immunologic Memory Immunological memory Immunology Immunoregulation Inflammation Interferon Interleukin Interleukin 17 Italy - epidemiology Lymphocyte Activation Lymphocyte Count Lymphocyte differentiation Lymphocytes Lymphocytes T Male Memory cells Middle Aged Mitochondria Pandemics PD-1 protein Peripheral blood Pneumonia Pneumonia, Viral - blood Pneumonia, Viral - immunology Pneumonia, Viral - pathology Public health SARS-CoV-2 Senescence Severe acute respiratory syndrome coronavirus 2 T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism T-Lymphocyte Subsets - pathology Th17 Cells - immunology Th17 Cells - metabolism Th17 Cells - pathology Transcription factors Tumor necrosis factor Tumor necrosis factor-TNF Viral infection γ-Interferon

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    TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13104f0d28544740ae120c92d91f5bd4

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