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Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models...

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Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation

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TN_cdi_doaj_primary_oai_doaj_org_article_1bcb386aa1ca4013886e1505ff8f7c1c

Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation

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https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1bcb386aa1ca4013886e1505ff8f7c1c

Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation

Full title

Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation

Publisher

Switzerland: MDPI AG

Journal title

Antioxidants, 2021, Vol.11 (1), p.28

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1bcb386aa1ca4013886e1505ff8f7c1c

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

SCOPE AND CONTENTS

Contents

Curcumin shows a broad spectrum of activities of relevance in the treatment of Alzheimer's disease (AD); however, it is poorly absorbed and is also chemically and metabolically unstable, leading to a very low oral bioavailability. A small library of hybrid compounds designed as curcumin analogues and incorporating the key structural fragment of pip...

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Full title

Curcumin-Piperlongumine Hybrids with a Multitarget Profile Elicit Neuroprotection in In Vitro Models of Oxidative Stress and Hyperphosphorylation

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PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1bcb386aa1ca4013886e1505ff8f7c1c

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1bcb386aa1ca4013886e1505ff8f7c1c

OTHER IDENTIFIERS

ISSN

2076-3921

E-ISSN

2076-3921

DOI

10.3390/antiox11010028

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