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Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

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TN_cdi_doaj_primary_oai_doaj_org_article_2bf99c4671d44e71969d21873ef164c4

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

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https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2bf99c4671d44e71969d21873ef164c4

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Full title

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Publisher

England: Nature Publishing Group

Journal title

Nature communications, 2018, Vol.9 (1), p.250-14

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TN_cdi_doaj_primary_oai_doaj_org_article_2bf99c4671d44e71969d21873ef164c4

Language

English

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Adenosine diphosphate Adenosine Diphosphate Ribose - metabolism Adenosine triphosphate Adenosine Triphosphate - metabolism Basic Medicine Biological Sciences Biologiska vetenskaper Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer Cancer and Oncology Cancer och onkologi Cell and Molecular Biology Cell Biology Cell Line, Tumor Cell Nucleus - drug effects Cell Nucleus - metabolism Cell proliferation Cell Proliferation - drug effects Cell Proliferation - genetics Cell- och molekylärbiologi Cellbiologi Chromatin Chromatin remodeling Clinical Medicine Drug discovery and development Enzyme Inhibitors - chemistry Enzyme Inhibitors - metabolism Enzyme Inhibitors - pharmacology Female Gene expression Gene regulation Guanine HL-60 Cells Humans Inhibitors Klinisk medicin Medical and Health Sciences Medical Biotechnology Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) Medicin och hälsovetenskap Medicinsk bioteknologi Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) Medicinska och farmaceutiska grundvetenskaper Metabolism Molecular Structure Natural Sciences Naturvetenskap Progestin Progestins - metabolism Pyrophosphatases - antagonists & inhibitors Pyrophosphatases - genetics Pyrophosphatases - metabolism Ribose RNA Interference Sanitation Screening Signal Transduction - drug effects Signaling Substrate Specificity Substrates Target validation

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TN_cdi_doaj_primary_oai_doaj_org_article_2bf99c4671d44e71969d21873ef164c4

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