SLNSW-A Novel CD73 Inhibitor SHR170008 Suppresses Adeno...-TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

Full title: A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

Author/creator: Liu, Suxing, Li, Di, Liu, Jian, Wang, Huiyun, Horecny, Ivana, Shen, Ru, Zhang, Rumin, Wu, Heping, Hu, Qiyue, Zhao, Peng, Zhang, Fengqi, Yan, Yinfa, Feng, Jun, Zhuang, Linghang, Li, Jing, Zhang, Lianshan, Tao, Weikang.

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Record Identifier: TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

Language: English

Formats: Articles

Publishers: New Zealand: Taylor & Francis Ltd

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

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    A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

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    TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

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    A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

    A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

    Full title

    A Novel CD73 Inhibitor SHR170008 Suppresses Adenosine in Tumor and Enhances Anti-Tumor Activity with PD-1 Blockade in a Mouse Model of Breast Cancer

    Author / Creator

    Liu, Suxing ; Li, Di ; Liu, Jian ; Wang, Huiyun ; Horecny, Ivana ; Shen, Ru ; Zhang, Rumin ; Wu, Heping ; Hu, Qiyue ; Zhao, Peng ; Zhang, Fengqi ; Yan, Yinfa ; Feng, Jun ; Zhuang, Linghang ; Li, Jing ; Zhang, Lianshan ; Tao, Weikang

    Publisher

    New Zealand: Taylor & Francis Ltd

    Journal title

    OncoTargets and therapy, 2021, Vol.14, p.4561-4574

    Record Identifier

    TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

    Language

    English

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    Articles

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    Adenine Adenosine anti-PD-1 mAb Antigens Antitumor activity Antitumor agents Biomarkers Breast cancer Cancer therapies CD25 antigen CD73 antigen CD8 antigen Cell survival checkpoint blockade combination therapy Enzymes Flow cytometry Granzyme B Immune checkpoint inhibitors Immunotherapy Leukocytes (mononuclear) Ligands Lymphocytes Lymphocytes T Medical prognosis Melanoma Metastases Molecular modelling Monoclonal antibodies Original Research PD-1 protein Peripheral blood mononuclear cells Proteins Ribose small molecule inhibitor of cd73 Tumors Vascularization γ-Interferon

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    TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d649edff7504f63a79d510fa7ae7229

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