SLNSW-PLX8394, a new generation BRAF inhibitor, selecti...-TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation

Full title: PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation

Author/creator: Tutuka, Candani S A, Andrews, Miles C, Mariadason, John M, Ioannidis, Paul, Hudson, Christopher, Cebon, Jonathan, Behren, Andreas.

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Record Identifier: TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

Language: English

Formats: Articles

Publishers: England: BioMed Central Ltd

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

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    PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation

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    TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

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    PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

    PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation

    Full title

    PLX8394, a new generation BRAF inhibitor, selectively inhibits BRAF in colonic adenocarcinoma cells and prevents paradoxical MAPK pathway activation

    Author / Creator

    Tutuka, Candani S A ; Andrews, Miles C ; Mariadason, John M ; Ioannidis, Paul ; Hudson, Christopher ; Cebon, Jonathan ; Behren, Andreas

    Publisher

    England: BioMed Central Ltd

    Journal title

    Molecular cancer, 2017, Vol.16 (1), p.112-112

    Record Identifier

    TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

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    English

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    Articles

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    Subjects and topics

    Activation Activation analysis Adenocarcinoma Adenocarcinoma - drug therapy Adenocarcinoma - metabolism Analysis Antimitotic agents Antineoplastic agents Antineoplastic Agents - pharmacology Biotechnology BRAF Cancer Case studies Cell growth Cell Line, Tumor Cell lines Cell proliferation Cell Proliferation - drug effects Colonic Neoplasms - drug therapy Colonic Neoplasms - metabolism Colorectal cancer Colorectal carcinoma Dosage and administration Drug therapy Heterocyclic Compounds, 2-Ring - pharmacology Humans Indoles - pharmacology Inhibitors K-Ras protein Lesions Letter to the Editor MAP kinase MAP Kinase Signaling System - drug effects MAPK pathway Melanoma Melanoma - drug therapy Melanoma - genetics Melanoma - pathology Metastases Metastasis Mutation Neoplasia Pancreatic cancer Paradoxical activation Patients Pharmacology Phosphorylation Promotion Protein kinase Protein Kinase Inhibitors - pharmacology Proto-Oncogene Proteins B-raf - antagonists & inhibitors Proto-Oncogene Proteins B-raf - genetics Proto-Oncogene Proteins B-raf - metabolism Ras protein Signal transduction Sulfonamides - pharmacology Treatment outcome

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    TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_52659a72efb14eaba7327e7008ad3690

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