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Synthesis of a New Class of Spirooxindole-Benzo[ b ]Thiophene-Based Molecules as Acetylcholinesteras...

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Synthesis of a New Class of Spirooxindole-Benzo[ b ]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors

Record identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6d467a7bf4044cbfb1d1e3af00d2ce94

Synthesis of a New Class of Spirooxindole-Benzo[ b ]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors

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https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d467a7bf4044cbfb1d1e3af00d2ce94

Synthesis of a New Class of Spirooxindole-Benzo[ b ]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors

Full title

Synthesis of a New Class of Spirooxindole-Benzo[ b ]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2020, Vol.25 (20), p.4671

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6d467a7bf4044cbfb1d1e3af00d2ce94

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

SCOPE AND CONTENTS

Contents

A series of new oxindole-based spiro-heterocycles bearing the benzo[
]thiophene motif were synthesized via a 1,3-dipolar cycloaddition reaction and their acetylcholinesterase (AChE) inhibitory activity was evaluated. All the synthesized compounds exhibited moderate inhibitory activities against AChE, while
was found to be the most active anal...

ALTERNATIVE TITLES

Full title

Synthesis of a New Class of Spirooxindole-Benzo[ b ]Thiophene-Based Molecules as Acetylcholinesterase Inhibitors

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6d467a7bf4044cbfb1d1e3af00d2ce94

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6d467a7bf4044cbfb1d1e3af00d2ce94

OTHER IDENTIFIERS

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules25204671

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