SLNSW-Design, Synthesis and In Vitro Evaluation of Spir...-TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

Full title: Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

Author/creator: Barakat, Assem, Mostafa, Ahmed, Ali, M., Al-Majid, Abdullah Mohammed, Domingo, Luis R., Kutkat, Omnia, Moatasim, Yassmin, Zia, Komal, Ul-Haq, Zaheer, Elshaier, Yaseen A. M. M..

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Record Identifier: TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

Language: English

Formats: Articles

Publishers: Basel: MDPI AG

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

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    Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

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    TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

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    Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

    Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

    Full title

    Design, Synthesis and In Vitro Evaluation of Spirooxindole-Based Phenylsulfonyl Moiety as a Candidate Anti-SAR-CoV-2 and MERS-CoV-2 with the Implementation of Combination Studies

    Author / Creator

    Barakat, Assem ; Mostafa, Ahmed ; Ali, M. ; Al-Majid, Abdullah Mohammed ; Domingo, Luis R. ; Kutkat, Omnia ; Moatasim, Yassmin ; Zia, Komal ; Ul-Haq, Zaheer ; Elshaier, Yaseen A. M. M.

    Publisher

    Basel: MDPI AG

    Journal title

    International journal of molecular sciences, 2022, Vol.23 (19), p.11861

    Record Identifier

    TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

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    English

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    Articles

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    ADMET Amines Antiviral activity Antiviral agents Coronaviruses COVID-19 Cycloaddition Cytotoxicity drug combination protocol Middle East respiratory syndrome molecular dynamic simulation (MDS) Pharmacophores Respiratory diseases SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 spirooxindole Stereoselectivity Synergistic effect Vinyl sulfone Viral diseases Viral infections

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    TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f7d12b0863e442f8b992b5bc12189ae

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