SLNSW-Andrographolide inhibits growth of human T-cell a...-TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

Full title: Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

Author/creator: Yang, Tingfang, Yao, Shuluan, Zhang, Xianfeng, Guo, Yan.

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Record Identifier: TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

Language: English

Formats: Articles

Publishers: New Zealand: Dove Medical Press Limited

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

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    Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

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    TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

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    Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

    Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

    Full title

    Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

    Author / Creator

    Yang, Tingfang ; Yao, Shuluan ; Zhang, Xianfeng ; Guo, Yan

    Publisher

    New Zealand: Dove Medical Press Limited

    Journal title

    Drug design, development and therapy, 2016, Vol.10 (Issue 1), p.1389-1397

    Record Identifier

    TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

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    English

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    Articles

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    1-Phosphatidylinositol 3-kinase Acute lymphoblastic leukemia Acute lymphocytic leukemia AKT AKT protein andrographolide Angiogenesis Animals Anticancer properties Apoptosis Apoptosis - drug effects Autophagy Breast cancer Burkitt lymphoma Cancer therapies Care and treatment Cell adhesion & migration Cell cycle Cell death Cell growth Cell Line, Tumor Cell Proliferation - drug effects Cellular signal transduction Children Cytotoxicity Development and progression Diterpenes - chemistry Diterpenes - pharmacology Dose-Response Relationship, Drug Down-Regulation - drug effects Flow cytometry Gene expression Genetic aspects Genetic regulation Health aspects Humans In vivo methods and tests Inhibition Inhibitors Jurkat cell Jurkat Cells Kinases Laboratory animals Leukemia Lymphatic leukemia Lymphocytes T Malignancy MAP kinase MAP Kinase Signaling System - drug effects Medical prognosis Mice Mice, Nude Neoplasms, Experimental - drug therapy Neoplasms, Experimental - metabolism Neoplasms, Experimental - pathology Original Research p38 Mitogen-Activated Protein Kinases - metabolism p53 Protein Phosphatidylinositol 3-Kinases - antagonists & inhibitors Phosphatidylinositol 3-Kinases - metabolism PI3K Plant products Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology Proteins Proto-Oncogene Proteins c-akt - antagonists & inhibitors Proto-Oncogene Proteins c-akt - metabolism Signal transduction Structure-Activity Relationship Tumors Up-Regulation - drug effects Western blotting Xenografts Xenotransplantation

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    TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4c48a5f05a444d7be93dc3cd20b71b0

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