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Physiological lentiviral vectors for the generation of improved CAR-T cells

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Record title

Physiological lentiviral vectors for the generation of improved CAR-T cells

Record identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c338abdeeff24c2185714739029ce627

Physiological lentiviral vectors for the generation of improved CAR-T cells

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https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c338abdeeff24c2185714739029ce627

Physiological lentiviral vectors for the generation of improved CAR-T cells

Full title

Physiological lentiviral vectors for the generation of improved CAR-T cells

Publisher

United States: Elsevier Inc

Journal title

Molecular therapy. Oncolytics, 2022, Vol.25, p.335-349

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c338abdeeff24c2185714739029ce627

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

SCOPE AND CONTENTS

Contents

Anti-CD19 chimeric antigen receptor (CAR)-T cells have achieved impressive outcomes for the treatment of relapsed and refractory B-lineage neoplasms. However, important limitations still remain due to severe adverse events (i.e., cytokine release syndrome and neuroinflammation) and relapse of 40%–50% of the treated patients. Most CAR-T cells are ge...

ALTERNATIVE TITLES

Full title

Physiological lentiviral vectors for the generation of improved CAR-T cells

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c338abdeeff24c2185714739029ce627

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c338abdeeff24c2185714739029ce627

OTHER IDENTIFIERS

ISSN

2372-7705

E-ISSN

2372-7705

DOI

10.1016/j.omto.2022.05.003

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