SLNSW-Combining PARP with ATR inhibition overcomes PARP...-TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

Full title: Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

Author/creator: Kim, Hyoung, Xu, Haineng, George, Erin, Hallberg, Dorothy, Kumar, Sushil, Jagannathan, Veena, Medvedev, Sergey, Kinose, Yasuto, Devins, Kyle, Verma, Priyanka, Ly, Kevin, Wang, Yifan, Greenberg, Roger A, Schwartz, Lauren, Johnson, Neil, Scharpf, Robert B, Mills, Gordon B, Zhang, Rugang, Velculescu, Victor E, Brown, Eric J, Simpkins, Fiona.

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Record Identifier: TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

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    Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

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    TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

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    Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

    Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

    Full title

    Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models

    Author / Creator

    Kim, Hyoung ; Xu, Haineng ; George, Erin ; Hallberg, Dorothy ; Kumar, Sushil ; Jagannathan, Veena ; Medvedev, Sergey ; Kinose, Yasuto ; Devins, Kyle ; Verma, Priyanka ; Ly, Kevin ; Wang, Yifan ; Greenberg, Roger A ; Schwartz, Lauren ; Johnson, Neil ; Scharpf, Robert B ; Mills, Gordon B ; Zhang, Rugang ; Velculescu, Victor E ; Brown, Eric J ; Simpkins, Fiona

    Publisher

    England: Nature Publishing Group

    Journal title

    Nature communications, 2020, Vol.11 (1), p.3726-3726

    Record Identifier

    TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

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    English

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    Articles

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    Animals Antineoplastic Agents - pharmacology Antineoplastic Combined Chemotherapy Protocols - pharmacology Antineoplastic Combined Chemotherapy Protocols - therapeutic use Apoptosis Apoptosis - drug effects Ataxia Telangiectasia Mutated Proteins - metabolism BRCA1 protein BRCA1 Protein - genetics BRCA1 Protein - metabolism BRCA2 Protein - metabolism Breast cancer Cancer Cancer therapeutic resistance Carcinoma, Ovarian Epithelial Cell Line, Tumor Chemotherapy CHK1 protein Cyclins - metabolism Drug Combinations Drug Resistance, Neoplasm - drug effects Drug Resistance, Neoplasm - genetics Female Gene Knockout Techniques Humans Inhibitors Mice, Inbred NOD Mice, SCID Mutation Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Platinum Platinum - pharmacology Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerase Inhibitors - pharmacology Protein Kinase Inhibitors - pharmacology Rad51 Recombinase - metabolism Reversion Sensitivity Stalling Stem Cells Xenograft Model Antitumor Assays Xenografts Xenotransplantation

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    TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

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    https://collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_cc35bbdbfeb9477db7745da1954cd683

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