SLNSW-PD-0332991, a CDK4/6 inhibitor, significantly pro...-TN_cdi_plos_journals_1439077343

PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

Full title: PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

Author/creator: Barton, Kelly L, Misuraca, Katherine, Cordero, Francisco, Dobrikova, Elena, Min, Hooney D, Gromeier, Matthias, Kirsch, David G, Becher, Oren J.

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Record Identifier: TN_cdi_plos_journals_1439077343

Language: English

Formats: Articles

Publishers: United States: Public Library of Science

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439077343

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    Record title

    PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

    Record identifier

    TN_cdi_plos_journals_1439077343

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    https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439077343

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    PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

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    https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439077343

    PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

    Full title

    PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

    Author / Creator

    Barton, Kelly L ; Misuraca, Katherine ; Cordero, Francisco ; Dobrikova, Elena ; Min, Hooney D ; Gromeier, Matthias ; Kirsch, David G ; Becher, Oren J

    Publisher

    United States: Public Library of Science

    Journal title

    PloS one, 2013, Vol.8 (10), p.e77639

    Record Identifier

    TN_cdi_plos_journals_1439077343

    Language

    English

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    Animals Antineoplastic Agents - pharmacology Brain cancer Brain stem Brain Stem Neoplasms - genetics Brain Stem Neoplasms - mortality Brain Stem Neoplasms - pathology Brain Stem Neoplasms - therapy Brain tumors Cancer Cell cycle Cell Cycle Checkpoints - drug effects Cell Cycle Checkpoints - radiation effects Cell proliferation Cell Proliferation - drug effects Cell Proliferation - radiation effects Children Cyclin-dependent kinase 4 Cyclin-Dependent Kinase 4 - antagonists & inhibitors Cyclin-Dependent Kinase 4 - genetics Cyclin-Dependent Kinase 4 - metabolism Cyclin-Dependent Kinase 6 - antagonists & inhibitors Cyclin-Dependent Kinase 6 - genetics Cyclin-Dependent Kinase 6 - metabolism Cyclin-Dependent Kinase Inhibitor p16 - deficiency Cyclin-Dependent Kinase Inhibitor p16 - genetics Cyclin-dependent kinase inhibitors Cyclin-dependent kinases Cyclins Diagnosis Disease Models, Animal Drug Administration Schedule Drug therapy Gamma Rays Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - radiation effects Genetic engineering Genetically modified organisms Glioma Glioma - genetics Glioma - mortality Glioma - pathology Glioma - therapy Gliomas Inhibitors INK4 protein Kinases Mice Mutation Oncogene Proteins, Fusion - deficiency Oncogene Proteins, Fusion - genetics p53 Protein Piperazines - pharmacology Platelet-derived growth factor Proto-Oncogene Proteins c-sis - genetics Proto-Oncogene Proteins c-sis - metabolism Pyridines - pharmacology Radiation Radiation dosage Radiation therapy Retina Retinoblastoma Retinoblastoma Protein - genetics Retinoblastoma Protein - metabolism Signal Transduction Survival Survival Analysis Tumors

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    TN_cdi_plos_journals_1439077343

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    https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1439077343

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