SLNSW-Inhibiting DNA methylation activates cancer testi...-TN_cdi_plos_journals_1910480734

Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

Full title: Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

Author/creator: Siebenkäs, Cornelia, Chiappinelli, Katherine B, Guzzetta, Angela A, Sharma, Anup, Jeschke, Jana, Vatapalli, Rajita, Baylin, Stephen B, Ahuja, Nita.

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Record Identifier: TN_cdi_plos_journals_1910480734

Language: English

Formats: Articles

Publishers: United States: Public Library of Science

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910480734

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    Record title

    Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

    Record identifier

    TN_cdi_plos_journals_1910480734

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910480734

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    Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

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    https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910480734

    Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

    Full title

    Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

    Author / Creator

    Siebenkäs, Cornelia Chiappinelli, Katherine B Guzzetta, Angela A Sharma, Anup Jeschke, Jana Vatapalli, Rajita

    Publisher

    United States: Public Library of Science

    Journal title

    PloS one, 2017, Vol.12 (6), p.e0179501-e0179501

    Record Identifier

    TN_cdi_plos_journals_1910480734

    Language

    English

    Formats

    Articles

    Publication information

    Publisher

    United States: Public Library of Science

    Subjects

    Subjects and topics

    Animal models Animals Antigen presentation Antigen Presentation - genetics Antigen processing Antigens Antigens, Neoplasm - biosynthesis Antigens, Neoplasm - genetics Antigens, Neoplasm - immunology Biology and life sciences Biotechnology Caco-2 Cells Cancer Cancer therapies CD58 antigen Cell cycle Colon Colon cancer Colonic Neoplasms - genetics Colonic Neoplasms - immunology Colonic Neoplasms - metabolism Colonic Neoplasms - pathology Deoxyribonucleic acid Development and progression DNA DNA methylation DNA Methylation - genetics DNA Methylation - immunology DNA, Neoplasm - genetics DNA, Neoplasm - immunology DNA, Neoplasm - metabolism Drug dosages Epigenetics Female Gene expression Genetic aspects Genomes Humans Immune system Immunotherapy Inhibition Inhibitors Male Medical innovations Medicine Medicine and Health Sciences Melanoma Methylation Mice Ovarian cancer Ovarian carcinoma Ovarian Neoplasms - genetics Ovarian Neoplasms - immunology Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Patients Physiological aspects Ribonucleic acid RNA Solid tumors Surgery Testicular Neoplasms - genetics Testicular Neoplasms - immunology Testicular Neoplasms - metabolism Testicular Neoplasms - pathology Therapy Tissues Tumor antigens Tumor cell lines Tumor cells Tumors

    More information

    — SCOPE AND CONTENTS

    Contents

    Innovative therapies for solid tumors are urgently needed. Recently, therapies that harness the host immune system to fight cancer cells have successfully treated a subset of patients with solid tumors. These responses have been strong and durable but observed in subsets of patients. Work from our group and others has shown that epigenetic therapy,...

    — ALTERNATIVE TITLES

    Full title

    Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells

    — AUTHORS, ARTISTS AND CONTRIBUTORS

    Author / Creator

    Identifiers

    — PRIMARY IDENTIFIERS

    Record Identifier

    TN_cdi_plos_journals_1910480734

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910480734

    — OTHER IDENTIFIERS

    ISSN

    1932-6203

    E-ISSN

    1932-6203

    DOI

    10.1371/journal.pone.0179501

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