SLNSW-Dabrafenib in patients with melanoma, untreated b...-TN_cdi_proquest_journals_1015775804

Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

Full title: Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

Author/creator: Falchook, Gerald S, Dr, Long, Georgina V, PhD, Kurzrock, Razelle, Prof, Kim, Kevin B, MD, Arkenau, Tobias H, PhD, Brown, Michael P, PhD, Hamid, Omid, MD, Infante, Jeffrey R, MD, Millward, Michael, MD, Pavlick, Anna C, MD, O’Day, Steven J, MD, Blackman, Samuel C, PhD, Curtis, C Martin, BA, Lebowitz, Peter, PhD, Ma, Bo, PhD, Ouellet, Daniele, PhD, Kefford, Richard F, Prof.

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Record Identifier: TN_cdi_proquest_journals_1015775804

Language: English

Formats: Articles

Publishers: Kidlington: Elsevier Ltd

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1015775804

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    Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

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    TN_cdi_proquest_journals_1015775804

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1015775804

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    Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1015775804

    Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

    Full title

    Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial

    Author / Creator

    Falchook, Gerald S, Dr ; Long, Georgina V, PhD ; Kurzrock, Razelle, Prof ; Kim, Kevin B, MD ; Arkenau, Tobias H, PhD ; Brown, Michael P, PhD ; Hamid, Omid, MD ; Infante, Jeffrey R, MD ; Millward, Michael, MD ; Pavlick, Anna C, MD ; O’Day, Steven J, MD ; Blackman, Samuel C, PhD ; Curtis, C Martin, BA ; Lebowitz, Peter, PhD ; Ma, Bo, PhD ; Ouellet, Daniele, PhD ; Kefford, Richard F, Prof

    Publisher

    Kidlington: Elsevier Ltd

    Journal title

    The Lancet (British edition), 2012, Vol.379 (9829), p.1893-1901

    Record Identifier

    TN_cdi_proquest_journals_1015775804

    Language

    English

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    Articles

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    Adult animal ovaries Antimitotic agents Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents - adverse effects Biological and medical sciences brain Brain Neoplasms - drug therapy Brain Neoplasms - secondary carcinoma Carcinoma, Squamous Cell - chemically induced Chemotherapy Clinical trials colorectal neoplasms Complications and side effects Dermatology Dosage and administration Drug Administration Schedule Drug therapy Fatigue - chemically induced Female Fever - chemically induced gastrointestinal system General aspects Genotype Humans Imidazoles - administration & dosage Imidazoles - adverse effects Indoles - administration & dosage Indoles - adverse effects Internal Medicine lung neoplasms Male Maximum Tolerated Dose Medical research Medical sciences Melanoma Melanoma - drug therapy Melanoma - genetics Melanoma - secondary Metastasis Middle Aged mutants Mutation Mutation - genetics Neoplasms - drug therapy Neoplasms - genetics Neurology ovarian neoplasms Oximes - administration & dosage Oximes - adverse effects patients pharmacokinetics Proto-Oncogene Proteins B-raf - antagonists & inhibitors Proto-Oncogene Proteins B-raf - genetics Skin Neoplasms - chemically induced Sulfonamides - administration & dosage Sulfonamides - adverse effects thyroid neoplasms titration Toxicity Treatment Outcome Tumors Tumors of the nervous system. Phacomatoses Tumors of the skin and soft tissue. Premalignant lesions

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    TN_cdi_proquest_journals_1015775804

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1015775804

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