SLNSW-First-in-human, phase I dose-escalation study of ...-TN_cdi_proquest_journals_1500908432

First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers

Full title: First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers

Author/creator: Saito, Kaku, Nagashima, Hirotaka, Noguchi, Kazuharu, Yoshisue, Kunihiro, Yokogawa, Tatsushi, Matsushima, Eiji, Tahara, Takeshi, Takagi, Shigeru.

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Record Identifier: TN_cdi_proquest_journals_1500908432

Language: English

Formats: Articles

Publishers: Berlin/Heidelberg: Springer Berlin Heidelberg

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1500908432

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    Record title

    First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers

    Record identifier

    TN_cdi_proquest_journals_1500908432

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1500908432

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    First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1500908432

    First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers

    Full title

    First-in-human, phase I dose-escalation study of single and multiple doses of a first-in-class enhancer of fluoropyrimidines, a dUTPase inhibitor (TAS-114) in healthy male volunteers

    Author / Creator

    Saito, Kaku ; Nagashima, Hirotaka ; Noguchi, Kazuharu ; Yoshisue, Kunihiro ; Yokogawa, Tatsushi ; Matsushima, Eiji ; Tahara, Takeshi ; Takagi, Shigeru

    Publisher

    Berlin/Heidelberg: Springer Berlin Heidelberg

    Journal title

    Cancer chemotherapy and pharmacology, 2014, Vol.73 (3), p.577-583

    Record Identifier

    TN_cdi_proquest_journals_1500908432

    Language

    English

    Formats

    Articles

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    Adult Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics Biological and medical sciences Cancer Cancer Research Chemotherapy Clinical trials Cohort Studies Cytochrome P-450 Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Fluorouracil - administration & dosage Fluorouracil - adverse effects Fluorouracil - pharmacokinetics Healthy Volunteers Humans Male Medical sciences Medicine Medicine & Public Health Oncology Original Article Pharmacology. Drug treatments Pharmacology/Toxicology Pyrimidine nucleotides Pyrophosphatases - antagonists & inhibitors Young Adult

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    TN_cdi_proquest_journals_1500908432

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1500908432

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