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A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

Full title: A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

Author/creator: Infante, Jeffrey R., Mendelson, David S., Burris, Howard A., Bendell, Johanna C., Tolcher, Anthony W., Gordon, Michael S., Gillenwater, Heidi H., Arastu-Kapur, Shirin, Wong, Hansen L., Papadopoulos, Kyriakos P..

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Record Identifier: TN_cdi_proquest_journals_1772049784

Language: English

Formats: Articles

Publishers: New York: Springer US

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1772049784

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    Record title

    A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

    Record identifier

    TN_cdi_proquest_journals_1772049784

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1772049784

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    A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1772049784

    A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

    Full title

    A first-in-human dose-escalation study of the oral proteasome inhibitor oprozomib in patients with advanced solid tumors

    Author / Creator

    Infante, Jeffrey R. ; Mendelson, David S. ; Burris, Howard A. ; Bendell, Johanna C. ; Tolcher, Anthony W. ; Gordon, Michael S. ; Gillenwater, Heidi H. ; Arastu-Kapur, Shirin ; Wong, Hansen L. ; Papadopoulos, Kyriakos P.

    Publisher

    New York: Springer US

    Journal title

    Investigational new drugs, 2016, Vol.34 (2), p.216-224

    Record Identifier

    TN_cdi_proquest_journals_1772049784

    Language

    English

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    Articles

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    Administration, Oral Adult Aged Aged, 80 and over Analysis Antineoplastic Agents - administration & dosage Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Bioavailability Cancer therapies Care and treatment Carfilzomib Clinical trials Colorectal cancer Complications and side effects Dosage and administration Dose-Response Relationship, Drug Drug dosages FDA approval Female Health aspects Hematology Humans Male Maximum Tolerated Dose Medicine Medicine & Public Health Middle Aged Multiple myeloma Neoplasm Staging Neoplasms - drug therapy Neoplasms - pathology Neutropenia Oligopeptides - adverse effects Oligopeptides - pharmacokinetics Oligopeptides - pharmacology Oligopeptides - therapeutic use Oncology Patients Pharmaceutical sciences Pharmacodynamics Pharmacokinetics Pharmacology/Toxicology Phase I Studies Protease inhibitors Proteasome Inhibitors - adverse effects Proteasome Inhibitors - pharmacokinetics Proteasome Inhibitors - pharmacology Proteasome Inhibitors - therapeutic use Small intestine Studies Thrombocytopenia Toxicity Tumors Vomiting

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    TN_cdi_proquest_journals_1772049784

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1772049784

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