SLNSW-Hepatocyte growth factor renders BRAF mutant huma...-TN_cdi_proquest_journals_1841777649

Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

Full title: Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

Author/creator: Rohrbeck, Leona, Gong, Jia-Nan, Lee, Erinna F, Kueh, Andrew J, Behren, Andreas, Tai, Lin, Lessene, Guillaume, Huang, David C S, Fairlie, Walter D, Strasser, Andreas, Herold, Marco J.

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Record Identifier: TN_cdi_proquest_journals_1841777649

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1841777649

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    Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

    Record identifier

    TN_cdi_proquest_journals_1841777649

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1841777649

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    Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1841777649

    Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

    Full title

    Hepatocyte growth factor renders BRAF mutant human melanoma cell lines resistant to PLX4032 by downregulating the pro-apoptotic BH3-only proteins PUMA and BIM

    Author / Creator

    Rohrbeck, Leona ; Gong, Jia-Nan ; Lee, Erinna F ; Kueh, Andrew J ; Behren, Andreas ; Tai, Lin ; Lessene, Guillaume ; Huang, David C S ; Fairlie, Walter D ; Strasser, Andreas ; Herold, Marco J

    Publisher

    England: Nature Publishing Group

    Journal title

    Cell death and differentiation, 2016, Vol.23 (12), p.2054-2062

    Record Identifier

    TN_cdi_proquest_journals_1841777649

    Language

    English

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    Apoptosis - drug effects Apoptosis Regulatory Proteins - metabolism Bcl-2-Like Protein 11 - metabolism bcl-X Protein - metabolism Cell Line, Tumor Down-Regulation - drug effects Drug Resistance, Neoplasm - drug effects Hepatocyte Growth Factor - pharmacology Humans Indoles - pharmacology Indoles - therapeutic use Melanoma - drug therapy Melanoma - genetics Melanoma - pathology Mutation - genetics Original Paper Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins B-raf - genetics Sulfonamides - pharmacology Sulfonamides - therapeutic use Up-Regulation - drug effects Vemurafenib

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    TN_cdi_proquest_journals_1841777649

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1841777649

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