SLNSW-A phase 1b study of transforming growth factor-be...-TN_cdi_proquest_journals_2068187583

A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma

Full title: A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma

Author/creator: Ikeda, Masafumi, Morimoto, Manabu, Tajimi, Masaomi, Inoue, Koichi, Benhadji, Karim A., Lahn, Michael M. F., Sakai, Daisuke.

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Record Identifier: TN_cdi_proquest_journals_2068187583

Language: English

Formats: Articles

Publishers: New York: Springer US

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068187583

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    Record title

    A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma

    Record identifier

    TN_cdi_proquest_journals_2068187583

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068187583

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    A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068187583

    A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma

    Full title

    A phase 1b study of transforming growth factor-beta receptor I inhibitor galunisertib in combination with sorafenib in Japanese patients with unresectable hepatocellular carcinoma

    Author / Creator

    Ikeda, Masafumi ; Morimoto, Manabu ; Tajimi, Masaomi ; Inoue, Koichi ; Benhadji, Karim A. ; Lahn, Michael M. F. ; Sakai, Daisuke

    Publisher

    New York: Springer US

    Journal title

    Investigational new drugs, 2019, Vol.37 (1), p.118-126

    Record Identifier

    TN_cdi_proquest_journals_2068187583

    Language

    English

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    Articles

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    Aged Aged, 80 and over Anticancer properties Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics Antineoplastic Combined Chemotherapy Protocols - therapeutic use Antitumor activity Carcinoma, Hepatocellular - drug therapy Carcinoma, Hepatocellular - enzymology Carcinoma, Hepatocellular - pathology Constraining Drug therapy Female Follow-Up Studies Galunisertib Genetic aspects Growth factors Hepatocellular carcinoma Hepatoma Humans Hypophosphatemia Japan Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - enzymology Liver Neoplasms - pathology Male Maximum Tolerated Dose Medicine Medicine & Public Health Middle Aged Oncology Patients Pharmacokinetics Pharmacology Pharmacology/Toxicology Phase I clinical trial Phase I Studies Phase transitions Prognosis Protein-serine/threonine kinase Pyrazoles - administration & dosage Quinolines - administration & dosage Receptor, Transforming Growth Factor-beta Type I - antagonists & inhibitors Safety Safety measures Sorafenib Sorafenib - administration & dosage Studies Targeted cancer therapy Threonine Tissue Distribution Toxicity Transforming growth factor-b

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    TN_cdi_proquest_journals_2068187583

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2068187583

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