SLNSW-A next-generation tumor-targeting IL-2 preferenti...-TN_cdi_proquest_journals_2281950730

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 + T-cell response and effective tumor control

Full title: A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 + T-cell response and effective tumor control

Author/creator: Sun, Zhichen, Ren, Zhenhua, Yang, Kaiting, Liu, Zhida, Cao, Shuaishuai, Deng, Sisi, Xu, Lily, Liang, Yong, Guo, Jingya, Bian, Yingjie, Xu, Hairong, Shi, Jiyun, Wang, Fan, Fu, Yang-Xin, Peng, Hua.

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Record Identifier: TN_cdi_proquest_journals_2281950730

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2281950730

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    A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 + T-cell response and effective tumor control

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    TN_cdi_proquest_journals_2281950730

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2281950730

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    A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 + T-cell response and effective tumor control

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2281950730

    A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 + T-cell response and effective tumor control

    Full title

    A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8 + T-cell response and effective tumor control

    Author / Creator

    Sun, Zhichen ; Ren, Zhenhua ; Yang, Kaiting ; Liu, Zhida ; Cao, Shuaishuai ; Deng, Sisi ; Xu, Lily ; Liang, Yong ; Guo, Jingya ; Bian, Yingjie ; Xu, Hairong ; Shi, Jiyun ; Wang, Fan ; Fu, Yang-Xin ; Peng, Hua

    Publisher

    England: Nature Publishing Group

    Journal title

    Nature communications, 2019, Vol.10 (1), p.3874-12

    Record Identifier

    TN_cdi_proquest_journals_2281950730

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    English

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    Articles

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    Animals Antibodies Anticancer properties Antineoplastic Agents, Immunological - pharmacology Antineoplastic Agents, Immunological - therapeutic use Antitumor activity B7-H1 Antigen - antagonists & inhibitors B7-H1 Antigen - immunology Binding Biocompatibility Biophysics Cancer Cancer therapies CD122 antigen CD25 antigen CD8 antigen Cell Line, Tumor - transplantation Cetuximab - pharmacology Cetuximab - therapeutic use Cytokines Cytotoxicity Disease Models, Animal Drug Resistance, Neoplasm - drug effects Drug Resistance, Neoplasm - immunology Drug Screening Assays, Antitumor Drug Synergism FDA approval Growth factors Humans Immune checkpoint Immunoconjugates - genetics Immunoconjugates - pharmacology Immunoconjugates - therapeutic use Immunology Immunotherapy Interleukin 2 Interleukin-2 - genetics Interleukin-2 - pharmacology Interleukin-2 - therapeutic use Interleukin-2 Receptor alpha Subunit - immunology Interleukin-2 Receptor alpha Subunit - metabolism Interleukin-2 Receptor beta Subunit - immunology Interleukin-2 Receptor beta Subunit - metabolism Kinases Laboratories Lymphocytes Lymphocytes T Lymphocytes, Tumor-Infiltrating - drug effects Lymphocytes, Tumor-Infiltrating - immunology Melanoma Mutation Neoplasms - drug therapy Neoplasms - immunology Neoplasms - pathology Receptor, ErbB-2 - antagonists & inhibitors Receptor, ErbB-2 - immunology Recombinant Proteins - genetics Recombinant Proteins - pharmacology Recombinant Proteins - therapeutic use T-Lymphocytes, Cytotoxic - drug effects T-Lymphocytes, Cytotoxic - immunology Therapy Toxicity Treatment Outcome Tumors

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    TN_cdi_proquest_journals_2281950730

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