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The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

Full title: The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

Author/creator: Helleday, Thomas.

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Record Identifier: TN_cdi_proquest_journals_2299146380

Language: English

Formats: Articles

Publishers: United States: Elsevier B.V

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2299146380

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    Record title

    The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

    Record identifier

    TN_cdi_proquest_journals_2299146380

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2299146380

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    The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

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    The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

    Full title

    The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings

    Author / Creator

    Helleday, Thomas

    Publisher

    United States: Elsevier B.V

    Journal title

    Molecular oncology, 2011, Vol.5 (4), p.387-393

    Record Identifier

    TN_cdi_proquest_journals_2299146380

    Language

    English

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    Articles

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    Analysis Animals Base excision repair BRCA1 BRCA1 protein BRCA1 Protein - antagonists & inhibitors BRCA1 Protein - genetics BRCA1 Protein - metabolism BRCA2 BRCA2 protein BRCA2 Protein - antagonists & inhibitors BRCA2 Protein - genetics BRCA2 Protein - metabolism Cancer Councils Deoxyribonucleic acid DNA DNA biosynthesis DNA Breaks, Double-Stranded DNA Breaks, Single-Stranded DNA damage DNA double-strand breaks DNA Repair DNA Replication Genes Homologous recombination Humans Intermediates Lethality Models, Genetic Natural Sciences Naturvetenskap Neoplasms - genetics Neoplasms - pathology Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerase Inhibitors Poly(ADP-ribose) Polymerases - metabolism Proteins Recombination, Genetic Replication forks Review Reviews Ribose Roles Stalled replication fork Synthetic lethality Tumors

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    TN_cdi_proquest_journals_2299146380

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2299146380

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