SLNSW-Discovery of Novel Pyridazine-Based Cyclooxygenas...-TN_cdi_proquest_journals_2396589769

Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

Full title: Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

Author/creator: Khan, Abida, Diwan, Anupama, Thabet, Hamdy Kh, Imran, Mohd, Bakht, Md Afroz.

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Record Identifier: TN_cdi_proquest_journals_2396589769

Language: English

Formats: Articles

Publishers: Switzerland: MDPI AG

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2396589769

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    Record title

    Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

    Record identifier

    TN_cdi_proquest_journals_2396589769

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2396589769

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    Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2396589769

    Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

    Full title

    Discovery of Novel Pyridazine-Based Cyclooxygenase-2 Inhibitors with a Promising Gastric Safety Profile

    Author / Creator

    Khan, Abida ; Diwan, Anupama ; Thabet, Hamdy Kh ; Imran, Mohd ; Bakht, Md Afroz

    Publisher

    Switzerland: MDPI AG

    Journal title

    Molecules (Basel, Switzerland), 2020, Vol.25 (9), p.2002

    Record Identifier

    TN_cdi_proquest_journals_2396589769

    Language

    English

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    Articles

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    4-thiazolidinone Acids Aldehydes Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Anti-Ulcer Agents - chemistry Anti-Ulcer Agents - pharmacology Arthritis Celecoxib Chemical Phenomena COX-2 inhibitors Cyclooxygenase 2 Inhibitors - chemistry Cyclooxygenase 2 Inhibitors - pharmacology Cyclooxygenase-1 Cyclooxygenase-2 Dose-Response Relationship, Drug Drug Discovery - methods Enzymes Heart failure Hydrazines Hydrazones Hydrogen Bonding In vivo methods and tests Indomethacin Inflammation Inflammatory diseases Inhibitors Lipid peroxidation Lipid Peroxidation - drug effects Lipids Lipinski’s rule Mathematical analysis Models, Molecular Molecular Conformation Molecular docking Molecular Structure non-ulcerogenic Parameters Peroxidation pyridazine Pyridazines Pyridazines - pharmacology Safety Spectrum Analysis Structure-Activity Relationship thiazole

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    TN_cdi_proquest_journals_2396589769

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2396589769

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