SLNSW-Oroxindin inhibits macrophage NLRP3 inflammasome ...-TN_cdi_proquest_journals_2408527282

Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

Full title: Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

Author/creator: Liu, Qi, Zuo, Rui, Wang, Kai, Nong, Fei-Fei, Fu, Ya-Jun, Huang, Shao-Wei, Pan, Zeng-Feng, Zhang, Yi, Luo, Xia, Deng, Xiang-Liang, Zhang, Xiao-Xue, Zhou, Lian, Chen, Yang.

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Record Identifier: TN_cdi_proquest_journals_2408527282

Language: English

Formats: Articles

Publishers: United States: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2408527282

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    Record title

    Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

    Record identifier

    TN_cdi_proquest_journals_2408527282

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2408527282

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    Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2408527282

    Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

    Full title

    Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway

    Author / Creator

    Liu, Qi ; Zuo, Rui ; Wang, Kai ; Nong, Fei-Fei ; Fu, Ya-Jun ; Huang, Shao-Wei ; Pan, Zeng-Feng ; Zhang, Yi ; Luo, Xia ; Deng, Xiang-Liang ; Zhang, Xiao-Xue ; Zhou, Lian ; Chen, Yang

    Publisher

    United States: Nature Publishing Group

    Journal title

    Acta pharmacologica Sinica, 2020, Vol.41 (6), p.771-781

    Record Identifier

    TN_cdi_proquest_journals_2408527282

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    English

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    Administration, Oral Animals anti-inflammatory Antioxidants Carrier Proteins - antagonists & inhibitors Carrier Proteins - metabolism Caspase-1 Cell activation Chinese medicine Chromones - administration & dosage Chromones - pharmacology Colitis, Ulcerative - chemically induced Colitis, Ulcerative - drug therapy Colitis, Ulcerative - pathology Colon Dextran Dextran sulfate Dextran Sulfate - administration & dosage Dose-Response Relationship, Drug Drinking water Flavonoids Glucuronates - administration & dosage Glucuronates - pharmacology IL-1β Inflammasomes Inflammasomes - drug effects Inflammasomes - metabolism Inflammatory bowel disease Inflammatory bowel diseases Interleukin 18 Lipopolysaccharides Macrophages Macrophages - drug effects Macrophages - metabolism Male Mice Mice, Inbred C57BL NF-kappa B - antagonists & inhibitors NF-kappa B - metabolism NF-κB protein NF-κB signaling NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors NLR Family, Pyrin Domain-Containing 3 Protein - metabolism NLRP3 inflammasome Oligomerization oroxindin Signal transduction Structure-Activity Relationship Thioredoxins - antagonists & inhibitors Thioredoxins - metabolism Traditional Chinese medicine TXNIP Ulcerative colitis

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    TN_cdi_proquest_journals_2408527282

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2408527282

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