SLNSW-Design, synthesis, in vitro and in vivo evaluatio...-TN_cdi_proquest_journals_2463570878

Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease

Full title: Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease

Author/creator: Mo, Jun, Chen, Tingkai, Yang, Hongyu, Guo, Yan, Li, Qi, Qiao, Yuting, Lin, Hongzhi, Feng, Feng, Liu, Wenyuan, Chen, Yao, Liu, Zongliang, Sun, Haopeng.

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Record Identifier: TN_cdi_proquest_journals_2463570878

Language: English

Formats: Articles

Publishers: England: Taylor & Francis

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2463570878

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    Record title

    Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease

    Record identifier

    TN_cdi_proquest_journals_2463570878

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2463570878

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    Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2463570878

    Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease

    Full title

    Design, synthesis, in vitro and in vivo evaluation of benzylpiperidine-linked 1,3-dimethylbenzimidazolinones as cholinesterase inhibitors against Alzheimer's disease

    Author / Creator

    Mo, Jun ; Chen, Tingkai ; Yang, Hongyu ; Guo, Yan ; Li, Qi ; Qiao, Yuting ; Lin, Hongzhi ; Feng, Feng ; Liu, Wenyuan ; Chen, Yao ; Liu, Zongliang ; Sun, Haopeng

    Publisher

    England: Taylor & Francis

    Journal title

    Journal of enzyme inhibition and medicinal chemistry, 2020, Vol.35 (1), p.330-343

    Record Identifier

    TN_cdi_proquest_journals_2463570878

    Language

    English

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    Articles

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    1,3-dimethylbenzimidazolinone derivatives Acetylcholinesterase Acetylcholinesterase - metabolism Alzheimer Disease - drug therapy Alzheimer Disease - metabolism Alzheimer's disease Alzheimers disease Amyloid beta-Peptides - antagonists & inhibitors Amyloid beta-Peptides - metabolism Animals Antioxidants Antioxidants - chemical synthesis Antioxidants - chemistry Antioxidants - pharmacology Benzimidazoles - chemical synthesis Benzimidazoles - chemistry Benzimidazoles - pharmacology Butyrylcholinesterase - metabolism Cell Death - drug effects Cell Survival - drug effects cholinesterase inhibitor Cholinesterase inhibitors Cholinesterase Inhibitors - chemical synthesis Cholinesterase Inhibitors - chemistry Cholinesterase Inhibitors - pharmacology Dose-Response Relationship, Drug Drug Design Electrophorus Hep G2 Cells Hepatotoxicity Horses Humans Hydrogen peroxide Mice Mice, Inbred ICR Models, Molecular molecular docking Molecular modelling Molecular Structure Neurodegenerative diseases Neuroprotection PC12 Cells Peptide Fragments - antagonists & inhibitors Peptide Fragments - metabolism Pheochromocytoma cells Protein Aggregates - drug effects Rats Research Paper Scopolamine structural modification Structure-Activity Relationship Tacrine

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    TN_cdi_proquest_journals_2463570878

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2463570878

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