SLNSW-The PD-1 expression balance between effector and ...-TN_cdi_proquest_journals_2475061487

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Full title: The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Author/creator: Kumagai, Shogo, Togashi, Yosuke, Kamada, Takahiro, Sugiyama, Eri, Nishinakamura, Hitomi, Takeuchi, Yoshiko, Vitaly, Kochin, Itahashi, Kota, Maeda, Yuka, Matsui, Shigeyuki, Shibahara, Takuma, Yamashita, Yasuho, Irie, Takuma, Tsuge, Ayaka, Fukuoka, Shota, Kawazoe, Akihito, Udagawa, Hibiki, Kirita, Keisuke, Aokage, Keiju, Ishii, Genichiro, Kuwata, Takeshi, Nakama, Kenta, Kawazu, Masahito, Ueno, Toshihide, Yamazaki, Naoya, Goto, Koichi, Tsuboi, Masahiro, Mano, Hiroyuki, Doi, Toshihiko, Shitara, Kohei, Nishikawa, Hiroyoshi.

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Record Identifier: TN_cdi_proquest_journals_2475061487

Language: English

Formats: Articles

Publishers: United States: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2475061487

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    Record title

    The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

    Record identifier

    TN_cdi_proquest_journals_2475061487

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2475061487

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    The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2475061487

    The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

    Full title

    The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

    Author / Creator

    Kumagai, Shogo ; Togashi, Yosuke ; Kamada, Takahiro ; Sugiyama, Eri ; Nishinakamura, Hitomi ; Takeuchi, Yoshiko ; Vitaly, Kochin ; Itahashi, Kota ; Maeda, Yuka ; Matsui, Shigeyuki ; Shibahara, Takuma ; Yamashita, Yasuho ; Irie, Takuma ; Tsuge, Ayaka ; Fukuoka, Shota ; Kawazoe, Akihito ; Udagawa, Hibiki ; Kirita, Keisuke ; Aokage, Keiju ; Ishii, Genichiro ; Kuwata, Takeshi ; Nakama, Kenta ; Kawazu, Masahito ; Ueno, Toshihide ; Yamazaki, Naoya ; Goto, Koichi ; Tsuboi, Masahiro ; Mano, Hiroyuki ; Doi, Toshihiko ; Shitara, Kohei ; Nishikawa, Hiroyoshi

    Publisher

    United States: Nature Publishing Group

    Journal title

    Nature immunology, 2020, Vol.21 (11), p.1346-1358

    Record Identifier

    TN_cdi_proquest_journals_2475061487

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    English

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    Antigens - chemistry Antigens - immunology Apoptosis Biomarkers Biomarkers, Tumor Cancer Care and treatment CD28 Antigens - metabolism CD8 antigen CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Cell death Cellular proteins Effector cells Enzymes Gene expression Gene Expression Regulation - drug effects Genetic aspects Health aspects Humans Immune checkpoint Immune Checkpoint Inhibitors - pharmacology Immune Checkpoint Inhibitors - therapeutic use Immunomodulation Immunoregulation Immunosuppression Immunotherapy Lymphocyte Activation - immunology Lymphocytes Lymphocytes T Lymphocytes, Tumor-Infiltrating - immunology Lymphocytes, Tumor-Infiltrating - metabolism Medical colleges Molecular Targeted Therapy Neoplasm Metastasis Neoplasm Staging Neoplasms - drug therapy Neoplasms - etiology Neoplasms - metabolism Neoplasms - mortality PD-1 protein PD-L1 protein Peptides - chemistry Peptides - immunology Pharmaceutical industry Prognosis Programmed Cell Death 1 Receptor - antagonists & inhibitors Programmed Cell Death 1 Receptor - genetics Programmed Cell Death 1 Receptor - metabolism Reactive Oxygen Species - metabolism Receptors, Antigen, T-Cell - metabolism Regulation Signal Transduction T cells T-Lymphocytes, Regulatory - drug effects T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Treatment Outcome Tumor microenvironment Tumor Microenvironment - immunology

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    TN_cdi_proquest_journals_2475061487

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2475061487

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