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Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β -Glucuronidase Inhibitors: In Vitro and In Silico Studies

Full title: Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β -Glucuronidase Inhibitors: In Vitro and In Silico Studies

Author/creator: Iqbal, Sarosh, Shaikh, Nimra Naveed, Khan, Khalid Mohammed, Kiran, Shumaila, Naz, Sehrish, Ul-Haq, Zaheer, Perveen, Shahnaz, Choudhary, M Iqbal.

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Record Identifier: TN_cdi_proquest_journals_2739449052

Language: English

Formats: Articles

Publishers: Switzerland: MDPI AG

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739449052

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    Record title

    Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β -Glucuronidase Inhibitors: In Vitro and In Silico Studies

    Record identifier

    TN_cdi_proquest_journals_2739449052

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739449052

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    Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β -Glucuronidase Inhibitors: In Vitro and In Silico Studies

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    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739449052

    Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β -Glucuronidase Inhibitors: In Vitro and In Silico Studies

    Full title

    Synthesis of 2-Aminopyrimidine Derivatives and Their Evaluation as β -Glucuronidase Inhibitors: In Vitro and In Silico Studies

    Author / Creator

    Iqbal, Sarosh ; Shaikh, Nimra Naveed ; Khan, Khalid Mohammed ; Kiran, Shumaila ; Naz, Sehrish ; Ul-Haq, Zaheer ; Perveen, Shahnaz ; Choudhary, M Iqbal

    Publisher

    Switzerland: MDPI AG

    Journal title

    Molecules (Basel, Switzerland), 2022, Vol.27 (22), p.7786

    Record Identifier

    TN_cdi_proquest_journals_2739449052

    Language

    English

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    Articles

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    2-Amino-4,6-dichloropyrimidine Amines Antioxidants Cancer catalyst-free synthesis Catalysts Colon cancer Crystal structure Enzyme Inhibitors - chemistry Enzymes Glucaric acid Glucuronidase - metabolism Hydrogen bonds in silico study Inhibitors Magnetic resonance spectroscopy Molecular Docking Simulation NMR NMR spectroscopy Nuclear magnetic resonance nucleophilic substitution reaction Proteins Software solvent-free synthesis Structure-Activity Relationship Substrates Triethylamine Urinary tract β-glucuronidase inhibitors

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    TN_cdi_proquest_journals_2739449052

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2739449052

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