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The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

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TN_cdi_proquest_miscellaneous_1751215637

The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

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https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751215637

The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

Full title

The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2015, Vol.16 (1), p.25-35

Record Identifier

TN_cdi_proquest_miscellaneous_1751215637

Language

English

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Administration, Oral Aged Antimitotic agents Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Aromatase Inhibitors - administration & dosage Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Blood Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - enzymology Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Cancer therapies Cardiovascular disease Care and treatment Cell cycle Cyclin D1 - genetics Cyclin-Dependent Kinase 4 - antagonists & inhibitors Cyclin-Dependent Kinase 4 - metabolism Cyclin-Dependent Kinase 6 - antagonists & inhibitors Cyclin-Dependent Kinase 6 - metabolism Cyclin-Dependent Kinase Inhibitor p16 - genetics Disease-Free Survival Drug Administration Schedule Drug dosages Estrogen Europe Female Fractures Gene amplification Hematology, Oncology and Palliative Medicine Humans Intention to Treat Analysis Middle Aged Molecular Targeted Therapy Nitriles - administration & dosage North America Oncology, Experimental Pain Phosphotransferases Piperazines - administration & dosage Postmenopause Proportional Hazards Models Protein Kinase Inhibitors - administration & dosage Pyridines - administration & dosage Receptor, ErbB-2 - analysis Receptor, ErbB-2 - genetics Receptors, Estrogen - analysis Regulation Republic of Korea South Africa Time Factors Treatment Outcome Triazoles - administration & dosage Womens health

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TN_cdi_proquest_miscellaneous_1751215637

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https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751215637

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