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Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription

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TN_cdi_proquest_miscellaneous_864953517

Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription

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https://collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_864953517

Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription

Full title

Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription

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Basingstoke: Nature Publishing Group

Journal title

Oncogene, 2010, Vol.29 (43), p.5775-5784

Record Identifier

TN_cdi_proquest_miscellaneous_864953517

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English

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5-aza-2'-deoxycytidine Antimetabolites, Antineoplastic - pharmacology Antisense Elements (Genetics) - drug effects Antisense Elements (Genetics) - metabolism Antisense therapy Azacitidine - analogs & derivatives Azacitidine - pharmacology Azacytidine Biological and medical sciences Blotting, Western c-Met protein Cancer Care and treatment Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Chromatin Immunoprecipitation Cytosine Demethylation Deoxyribonucleic acid DNA DNA Methylation - drug effects DNA Methylation - genetics DNA methyltransferase Epigenetics Fundamental and applied biological sciences. Psychology Gene expression Gene Expression - drug effects Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - genetics Gene silencing Genetic aspects Genetic Loci Genetics Genic rearrangement. Recombination. Transposable element HCT116 Cells Health aspects HL-60 Cells Humans Inhibitor drugs Long interspersed nucleotide elements Long Interspersed Nucleotide Elements - drug effects Long Interspersed Nucleotide Elements - genetics Methods Methylation Molecular and cellular biology Molecular genetics Patient outcomes Physiological aspects Promoter Regions, Genetic - drug effects Promoter Regions, Genetic - genetics Properties Proto-Oncogene Proteins c-met - genetics Proto-Oncogene Proteins c-met - metabolism Reverse Transcriptase Polymerase Chain Reaction Signal transduction Signal Transduction - drug effects Signal Transduction - genetics Transcription Transcription, Genetic - drug effects Transcription, Genetic - genetics Transcription. Transcription factor. Splicing. Rna processing Transfection Tumor suppressor genes Tumors

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TN_cdi_proquest_miscellaneous_864953517

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