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Longevity effect of IGF‐1R+/− mutation depends on genetic background‐specific receptor activation

Full title: Longevity effect of IGF‐1R+/− mutation depends on genetic background‐specific receptor activation

Author/creator: Xu, Jie, Gontier, Géraldine, Chaker, Zayna, Lacube, Philippe, Dupont, Joëlle, Holzenberger, Martin.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

Language: English

Formats: Articles

Publishers: England: Wiley Subscription Services, Inc

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

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    Record title

    Longevity effect of IGF‐1R+/− mutation depends on genetic background‐specific receptor activation

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

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    Longevity effect of IGF‐1R+/− mutation depends on genetic background‐specific receptor activation

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

    Longevity effect of IGF‐1R+/− mutation depends on genetic background‐specific receptor activation

    Full title

    Longevity effect of IGF‐1R+/− mutation depends on genetic background‐specific receptor activation

    Author / Creator

    Xu, Jie ; Gontier, Géraldine ; Chaker, Zayna ; Lacube, Philippe ; Dupont, Joëlle ; Holzenberger, Martin

    Publisher

    England: Wiley Subscription Services, Inc

    Journal title

    Aging cell, 2014, Vol.13 (1), p.19-28

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

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    English

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    Animals Body Size - drug effects Dextrose Female gene knockout Genetic aspects Genetic background Genetic research Genetics Glucose Glucose - metabolism Heterozygote IGF-I Insulin Insulin Receptor Substrate Proteins - metabolism Insulin-like growth factors IRS Life Sciences lifespan Longevity - drug effects Longevity - genetics Lubrication and lubricants Male Mice Mice, Inbred C57BL Mice, Knockout Models, Biological Mutation Mutation - genetics Original Oxidative Stress - drug effects Paraquat - toxicity Phosphotyrosine - metabolism Receptor, IGF Type 1 - genetics Signal Transduction - drug effects Somatomedins - metabolism stress resistance

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4326867

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