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MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

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Record title

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

Record identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

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https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

Full title

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

Publisher

England: Nature Publishing Group

Journal title

Nature (London), 2015, Vol.521 (7553), p.537-540

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

SCOPE AND CONTENTS

Contents

Appropriate repair of DNA lesions and the inhibition of DNA repair activities at telomeres are crucial to prevent genomic instability. By fuelling the generation of genetic alterations and by compromising cell viability, genomic instability is a driving force in cancer and ageing. Here we identify MAD2L2 (also known as MAD2B or REV7) through functi...

ALTERNATIVE TITLES

Full title

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296

OTHER IDENTIFIERS

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature14216

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