SLNSW-Cardiac Safety of TGF-β Receptor I Kinase Inhibit...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

Full title: Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

Author/creator: Kovacs, Richard J., Maldonado, Giuliana, Azaro, Analia, Fernández, Maria S., Romero, Federico L., Sepulveda-Sánchez, Juan M., Corretti, Mary, Carducci, Michael, Dolan, Melda, Gueorguieva, Ivelina, Cleverly, Ann L., Pillay, N. Sokalingum, Baselga, Jose, Lahn, Michael M..

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

Language: English

Formats: Articles

Publishers: New York: Springer US

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

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    Record title

    Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

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    Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

    Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

    Full title

    Cardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study

    Author / Creator

    Kovacs, Richard J. ; Maldonado, Giuliana ; Azaro, Analia ; Fernández, Maria S. ; Romero, Federico L. ; Sepulveda-Sánchez, Juan M. ; Corretti, Mary ; Carducci, Michael ; Dolan, Melda ; Gueorguieva, Ivelina ; Cleverly, Ann L. ; Pillay, N. Sokalingum ; Baselga, Jose ; Lahn, Michael M.

    Publisher

    New York: Springer US

    Journal title

    Cardiovascular toxicology, 2015, Vol.15 (4), p.309-323

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

    Language

    English

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    Articles

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    Adult Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biomarkers - blood Biomedical and Life Sciences Biomedicine Blood Pressure - drug effects Cardiac safety Cardiology Echocardiography, Doppler Electrocardiography Female First-in-human dose study Glioma Heart Diseases - blood Heart Diseases - chemically induced Heart Diseases - diagnostic imaging Humans Lomustine - administration & dosage LY2157299 Male Middle Aged Neoplasms - drug therapy Neoplasms - enzymology Neoplasms - pathology Pharmacology/Toxicology Prospective Studies Protein Kinase Inhibitors - administration & dosage Protein Kinase Inhibitors - adverse effects Protein-Serine-Threonine Kinases - antagonists & inhibitors Protein-Serine-Threonine Kinases - metabolism Pyrazoles - administration & dosage Pyrazoles - adverse effects Quinolines - administration & dosage Quinolines - adverse effects Receptors, Transforming Growth Factor beta - antagonists & inhibitors Receptors, Transforming Growth Factor beta - metabolism Risk Assessment Risk Factors Signal Transduction - drug effects Spain Time Factors Treatment Outcome Young Adult

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4575352

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