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Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

Full title: Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

Author/creator: Rabinovich, Shiran, Adler, Lital, Yizhak, Keren, Sarver, Alona, Silberman, Alon, Agron, Shani, Stettner, Noa, Sun, Qin, Brandis, Alexander, Helbling, Daniel, Korman, Stanley, Itzkovitz, Shalev, Dimmock, David, Ulitsky, Igor, Nagamani, Sandesh Cs, Ruppin, Eytan, Erez, Ayelet.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

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    Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

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    Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

    Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

    Full title

    Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

    Author / Creator

    Rabinovich, Shiran ; Adler, Lital ; Yizhak, Keren ; Sarver, Alona ; Silberman, Alon ; Agron, Shani ; Stettner, Noa ; Sun, Qin ; Brandis, Alexander ; Helbling, Daniel ; Korman, Stanley ; Itzkovitz, Shalev ; Dimmock, David ; Ulitsky, Igor ; Nagamani, Sandesh Cs ; Ruppin, Eytan ; Erez, Ayelet

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    England: Nature Publishing Group

    Journal title

    Nature (London), 2015, Vol.527 (7578), p.379-383

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

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    English

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    Articles

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    Animals Argininosuccinate Synthase Argininosuccinate Synthase - deficiency Argininosuccinate Synthase - metabolism Aspartate Aspartate Carbamoyltransferase - metabolism Aspartic Acid - metabolism Biosynthesis Calcium-Binding Proteins - antagonists & inhibitors Calcium-Binding Proteins - metabolism Cancer Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - metabolism Cell division Cell Line, Tumor Cell Proliferation Citrin Citrullinemia - metabolism Cytosol - metabolism Dihydroorotase - metabolism Down-Regulation Enzyme Activation Enzymes Fibroblasts Health aspects Humans Kinases Male Medical prognosis Metabolism Metabolites Mice Mice, SCID mTOR Neoplasms - enzymology Neoplasms - metabolism Neoplasms - pathology Oncology, Experimental Organic Anion Transporters - antagonists & inhibitors Organic Anion Transporters - metabolism Phosphorylation Physiological aspects pyrimidine synthesis Pyrimidines Pyrimidines - biosynthesis Studies TOR Serine-Threonine Kinases - metabolism Tumors Warburg effect

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4655447

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