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A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

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Record title

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

Record identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096816

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

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https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096816

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

Full title

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2016, Vol.126 (10), p.3837-3851

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096816

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

SCOPE AND CONTENTS

Contents

Wiskott-Aldrich syndrome (WAS) is associated with mutations in the WAS protein (WASp), which plays a critical role in the initiation of T cell receptor-driven (TCR-driven) actin polymerization. The clinical phenotype of WAS includes susceptibility to infection, allergy, autoimmunity, and malignancy and overlaps with the symptoms of dedicator of cyt...

ALTERNATIVE TITLES

Full title

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096816

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5096816

OTHER IDENTIFIERS

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI85774

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