SLNSW-Rapamycin inhibits the secretory phenotype of sen...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

Full title: Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

Author/creator: Wang, Rong, Yu, Zhen, Sunchu, Bharath, Shoaf, James, Dang, Ivana, Zhao, Stephanie, Caples, Kelsey, Bradley, Lynda, Beaver, Laura M., Ho, Emily, Löhr, Christiane V., Perez, Viviana I..

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

Language: English

Formats: Articles

Publishers: England: John Wiley & Sons, Inc

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

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    Record title

    Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

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    Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

    Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

    Full title

    Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

    Author / Creator

    Wang, Rong ; Yu, Zhen ; Sunchu, Bharath ; Shoaf, James ; Dang, Ivana ; Zhao, Stephanie ; Caples, Kelsey ; Bradley, Lynda ; Beaver, Laura M. ; Ho, Emily ; Löhr, Christiane V. ; Perez, Viviana I.

    Publisher

    England: John Wiley & Sons, Inc

    Journal title

    Aging cell, 2017, Vol.16 (3), p.564-574

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

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    English

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    Aging - genetics Aging - metabolism Animals Autophagy Autophagy - drug effects beta-Galactosidase - genetics beta-Galactosidase - metabolism Cell cycle Cell Proliferation - drug effects cell senescence Cellular Senescence - drug effects Cyclin-Dependent Kinase Inhibitor p16 - genetics Cyclin-Dependent Kinase Inhibitor p16 - metabolism Cyclin-dependent kinase inhibitor p21 Cyclin-Dependent Kinase Inhibitor p21 - genetics Cyclin-Dependent Kinase Inhibitor p21 - metabolism Cytokines Cytokines - genetics Cytokines - metabolism Female Fibroblasts Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - metabolism Gene Expression Regulation Genetic aspects GTP-binding protein Humans Inflammation Longevity Male Mice Mice, Knockout Muridae NF-E2-Related Factor 2 - deficiency NF-E2-Related Factor 2 - genetics Nrf2 NRF2 protein Original Phagocytosis Phenotype Physiological aspects Primary Cell Culture Rapamycin SASP Senescence Signal Transduction Sirolimus - pharmacology Skin Stat3 protein STAT3 Transcription Factor - genetics STAT3 Transcription Factor - metabolism TOR protein TOR Serine-Threonine Kinases - antagonists & inhibitors TOR Serine-Threonine Kinases - genetics TOR Serine-Threonine Kinases - metabolism β-Galactosidase β‐gal

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5418203

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