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Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infectio...

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Record title

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

Record identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531408

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

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https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531408

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

Full title

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2017, Vol.127 (8), p.3177-3188

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531408

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

SCOPE AND CONTENTS

Contents

Adoptive transfer of T cells engineered to express a hepatitis B virus-specific (HBV-specific) T cell receptor (TCR) may supplement HBV-specific immune responses in chronic HBV patients and facilitate HBV control. However, the risk of triggering unrestrained proliferation of permanently engineered T cells raises safety concerns that have hampered t...

ALTERNATIVE TITLES

Full title

Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531408

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5531408

OTHER IDENTIFIERS

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI93024

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