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Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

Full title: Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

Author/creator: Larson, Richard A., Yin, Ophelia Q. P., Hochhaus, Andreas, Saglio, Giuseppe, Clark, Richard E., Nakamae, Hirohisa, Gallagher, Neil J., Demirhan, Eren, Hughes, Timothy P., Kantarjian, Hagop M., le Coutre, Philipp D..

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

Language: English

Formats: Articles

Publishers: Berlin/Heidelberg: Springer-Verlag

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

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    Record title

    Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

    Record identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

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    Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

    Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

    Full title

    Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase

    Author / Creator

    Larson, Richard A. ; Yin, Ophelia Q. P. ; Hochhaus, Andreas ; Saglio, Giuseppe ; Clark, Richard E. ; Nakamae, Hirohisa ; Gallagher, Neil J. ; Demirhan, Eren ; Hughes, Timothy P. ; Kantarjian, Hagop M. ; le Coutre, Philipp D.

    Publisher

    Berlin/Heidelberg: Springer-Verlag

    Journal title

    European journal of clinical pharmacology, 2012, Vol.68 (5), p.723-733

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

    Language

    English

    Formats

    Articles

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    Subjects and topics

    Adolescent Adult Aged Aged, 80 and over Analysis Antimitotic agents Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents - blood Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - therapeutic use Bilirubin Bioavailability Biological and medical sciences Biological Availability Biomedical and Life Sciences Biomedicine Blood levels Care and treatment Chronic myeloid leukemia Cohort Studies Data processing Demography Dose-response effects Dose-Response Relationship, Drug Drug therapy EKG Electrocardiogram Electrocardiography Exposure-response relationship Female Fusion Proteins, bcr-abl - antagonists & inhibitors Hematologic and hematopoietic diseases Humans Leukemia Leukemia, Myeloid, Chronic-Phase - blood Leukemia, Myeloid, Chronic-Phase - drug therapy Leukemia, Myeloid, Chronic-Phase - metabolism Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Metabolic Clearance Rate Middle Aged Models, Biological Myelocytic leukemia Nilotinib Nonlymphoid leukemia Pharmacokinetics Pharmacokinetics and Disposition Pharmacology Pharmacology. Drug treatments Pharmacology/Toxicology Population pharmacokinetics Protein Kinase Inhibitors - administration & dosage Protein Kinase Inhibitors - blood Protein Kinase Inhibitors - pharmacokinetics Protein Kinase Inhibitors - therapeutic use Protein-Tyrosine Kinases - antagonists & inhibitors Pyrimidines - administration & dosage Pyrimidines - blood Pyrimidines - pharmacokinetics Pyrimidines - therapeutic use Questions and answers Regression analysis Universities and colleges Young Adult

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    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5557053

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