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Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

Full title: Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

Author/creator: Beckerman, Pazit, Bi-Karchin, Jing, Park, Ae Seo Deok, Qiu, Chengxiang, Dummer, Patrick D, Soomro, Irfana, Boustany-Kari, Carine M, Pullen, Steven S, Miner, Jeffrey H, Hu, Chien-An A, Rohacs, Tibor, Inoue, Kazunori, Ishibe, Shuta, Saleem, Moin A, Palmer, Matthew B, Cuervo, Ana Maria, Kopp, Jeffrey B, Susztak, Katalin.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

Language: English

Formats: Articles

Publishers: United States: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

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    Record title

    Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

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    Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

    Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

    Full title

    Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice

    Author / Creator

    Beckerman, Pazit ; Bi-Karchin, Jing ; Park, Ae Seo Deok ; Qiu, Chengxiang ; Dummer, Patrick D ; Soomro, Irfana ; Boustany-Kari, Carine M ; Pullen, Steven S ; Miner, Jeffrey H ; Hu, Chien-An A ; Rohacs, Tibor ; Inoue, Kazunori ; Ishibe, Shuta ; Saleem, Moin A ; Palmer, Matthew B ; Cuervo, Ana Maria ; Kopp, Jeffrey B ; Susztak, Katalin

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    United States: Nature Publishing Group

    Journal title

    Nature medicine, 2017, Vol.23 (4), p.429-438

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

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    English

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    Articles

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    albuminuria Albuminuria - genetics Alleles Animals APOL1 Apolipoprotein L1 Apolipoproteins Apolipoproteins - genetics Autophagy - genetics Azotemia - genetics Blotting, Western Endocytosis - genetics Endosomes - metabolism Fluorescent Antibody Technique Gene expression Genetic aspects Genetic Predisposition to Disease Genetic Variation glomerulosclerosis Glomerulosclerosis, Focal Segmental - genetics Glomerulosclerosis, Focal Segmental - pathology Health aspects HEK293 Cells HeLa Cells Humans Immunohistochemistry In Situ Nick-End Labeling Kidney diseases Kidney Glomerulus - metabolism Kidney Glomerulus - pathology Kidney Glomerulus - ultrastructure Lipoproteins, HDL - genetics Mice Mice, Transgenic Microscopy, Electron podocytes Podocytes - metabolism Podocytes - ultrastructure pyroptosis Renal Insufficiency, Chronic - genetics Renal Insufficiency, Chronic - pathology Risk factors

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5603285

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