SLNSW-A genome-editing strategy to treat β-hemoglobinop...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

Full title: A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

Author/creator: Traxler, Elizabeth A, Yao, Yu, Wang, Yong-Dong, Woodard, Kaitly J, Kurita, Ryo, Nakamura, Yukio, Hughes, Jim R, Hardison, Ross C, Blobel, Gerd A, Li, Chunliang, Weiss, Mitchell J.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

Language: English

Formats: Articles

Publishers: United States

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

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    Record title

    A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

    Record identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

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    A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

    A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

    Full title

    A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

    Author / Creator

    Traxler, Elizabeth A ; Yao, Yu ; Wang, Yong-Dong ; Woodard, Kaitly J ; Kurita, Ryo ; Nakamura, Yukio ; Hughes, Jim R ; Hardison, Ross C ; Blobel, Gerd A ; Li, Chunliang ; Weiss, Mitchell J

    Publisher

    United States

    Journal title

    Nature medicine, 2016, Vol.22 (9), p.987-990

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

    Language

    English

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    Articles

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    Subjects and topics

    Anemia, Sickle Cell - genetics Anemia, Sickle Cell - therapy beta-Globins - genetics beta-Thalassemia - genetics beta-Thalassemia - therapy CRISPR-Cas Systems Erythroid Precursor Cells Fetal Hemoglobin - genetics Fetal Hemoglobin - metabolism gamma-Globins - genetics Gene Editing - methods Hemoglobin A - genetics Hemoglobin A - metabolism Humans In Situ Hybridization, Fluorescence Mutagenesis, Site-Directed - methods Mutation Promoter Regions, Genetic - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism

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    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5706766

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