SLNSW-C-terminal modification of the insulin B:11–23 pe...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

Full title: C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

Author/creator: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS), Wang, Yang, Sosinowski, Tomasz, Novikov, Andrey, Crawford, Frances, Neau, David B., Yang, Junbao, Kwok, William W., Marrack, Philippa, Kappler, John W., Dai, Shaodong.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

Language: English

Formats: Articles

Publishers: United States: National Academy of Sciences

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

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    C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

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    C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

    C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

    Full title

    C-terminal modification of the insulin B:11–23 peptide creates superagonists in mouse and human type 1 diabetes

    Author / Creator

    Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) ; Wang, Yang ; Sosinowski, Tomasz ; Novikov, Andrey ; Crawford, Frances ; Neau, David B. ; Yang, Junbao ; Kwok, William W. ; Marrack, Philippa ; Kappler, John W. ; Dai, Shaodong

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    United States: National Academy of Sciences

    Journal title

    Proceedings of the National Academy of Sciences - PNAS, 2018, Vol.115 (1), p.162-167

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

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    English

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    Articles

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    60 APPLIED LIFE SCIENCES Agonists (Biochemistry) Alleles Animals Antigen presentation autoimmunity Biological Sciences CD4 antigen CD4-Positive T-Lymphocytes - immunology Cell activation Chains Crystal structure Diabetes Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Epitopes Epitopes - chemistry Epitopes - genetics Epitopes - immunology Grooves Health aspects Health risks Histocompatibility antigen HLA Histocompatibility Antigens Class II - chemistry Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology HLA-DQ Antigens - chemistry HLA-DQ Antigens - genetics HLA-DQ Antigens - immunology Human behavior Humans Insulin Insulin - chemistry Insulin - genetics Insulin - immunology Lymphocytes Lymphocytes T Major histocompatibility complex Mice Mice, Inbred NOD Mutation peptide presentation Peptides Physiological aspects Polymorphism posttranslational modification Protein Binding Protein Processing, Post-Translational - immunology Rodents self-tolerance Type 1 diabetes

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776820

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