SLNSW-Alcohol and endogenous aldehydes damage chromosom...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Full title: Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Author/creator: Garaycoechea, Juan I, Crossan, Gerry P, Langevin, Frédéric, Mulderrig, Lee, Louzada, Sandra, Yang, Fentang, Guilbaud, Guillaume, Park, Naomi, Roerink, Sophie, Nik-Zainal, Serena, Stratton, Michael R, Patel, Ketan J.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

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    Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

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    Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

    Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

    Full title

    Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

    Author / Creator

    Garaycoechea, Juan I ; Crossan, Gerry P ; Langevin, Frédéric ; Mulderrig, Lee ; Louzada, Sandra ; Yang, Fentang ; Guilbaud, Guillaume ; Park, Naomi ; Roerink, Sophie ; Nik-Zainal, Serena ; Stratton, Michael R ; Patel, Ketan J

    Publisher

    England: Nature Publishing Group

    Journal title

    Nature (London), 2018, Vol.553 (7687), p.171-177

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

    Language

    English

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    Articles

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    Subjects and topics

    Acetaldehyde Acetaldehyde - metabolism Alcohol Alcohol Dehydrogenase - deficiency Alcohol Dehydrogenase - genetics Alcohol Dehydrogenase - metabolism Alcoholic beverages Alcohols Aldehydes Animals Cell cycle Cell survival Cell Survival - drug effects Chromosome rearrangements Chromosomes Clonal deletion Damage accumulation Dehydrogenases Deoxyribonucleic acid DNA DNA Breaks, Double-Stranded - drug effects DNA damage DNA End-Joining Repair DNA repair Ethanol Ethanol - administration & dosage Ethanol - metabolism Ethanol - pharmacology Fanconi Anemia - genetics Fanconi Anemia - metabolism Fanconi Anemia - pathology Fanconi Anemia Complementation Group D2 Protein - deficiency Fanconi Anemia Complementation Group D2 Protein - genetics Fanconi Anemia Complementation Group D2 Protein - metabolism Female Gene Deletion Gene sequencing Genes, p53 - genetics Genomes Genomic instability Genomic Instability - drug effects Health aspects Hematopoietic Stem Cell Transplantation Hematopoietic stem cells Hematopoietic Stem Cells - drug effects Hematopoietic Stem Cells - metabolism Hematopoietic Stem Cells - pathology Ku Autoantigen - metabolism Male Mice Mice, Inbred C57BL Mutagenesis Mutation p53 Protein Recombination Recombinational DNA Repair - drug effects Stem cells Transplantation Tumor Suppressor Protein p53 - deficiency Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism Whole Genome Sequencing

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6047743

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