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A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

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Record title

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

Record identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

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https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

Full title

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

Publisher

England: Nature Publishing Group

Journal title

Nature (London), 2017, Vol.551 (7681), p.517-520

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

SCOPE AND CONTENTS

Contents

Checkpoint blockade immunotherapies enable the host immune system to recognize and destroy tumour cells. Their clinical activity has been correlated with activated T-cell recognition of neoantigens, which are tumour-specific, mutated peptides presented on the surface of cancer cells. Here we present a fitness model for tumours based on immune inter...

ALTERNATIVE TITLES

Full title

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6137806

OTHER IDENTIFIERS

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature24473

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