SLNSW-Shieldin complex promotes DNA end-joining and cou...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Full title: Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Author/creator: Dev, Harveer, Chiang, Ting-Wei Will, Lescale, Chloe, de Krijger, Inge, Martin, Alistair G, Pilger, Domenic, Coates, Julia, Sczaniecka-Clift, Matylda, Wei, Wenming, Ostermaier, Matthias, Herzog, Mareike, Lam, Jonathan, Shea, Abigail, Demir, Mukerrem, Wu, Qian, Yang, Fengtang, Fu, Beiyuan, Lai, Zhongwu, Balmus, Gabriel, Belotserkovskaya, Rimma, Serra, Violeta, O'Connor, Mark J, Bruna, Alejandra, Beli, Petra, Pellegrini, Luca, Caldas, Carlos, Deriano, Ludovic, Jacobs, Jacqueline J L, Galanty, Yaron, Jackson, Stephen P.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

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    Record title

    Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

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    Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

    Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

    Full title

    Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

    Author / Creator

    Dev, Harveer ; Chiang, Ting-Wei Will ; Lescale, Chloe ; de Krijger, Inge ; Martin, Alistair G ; Pilger, Domenic ; Coates, Julia ; Sczaniecka-Clift, Matylda ; Wei, Wenming ; Ostermaier, Matthias ; Herzog, Mareike ; Lam, Jonathan ; Shea, Abigail ; Demir, Mukerrem ; Wu, Qian ; Yang, Fengtang ; Fu, Beiyuan ; Lai, Zhongwu ; Balmus, Gabriel ; Belotserkovskaya, Rimma ; Serra, Violeta ; O'Connor, Mark J ; Bruna, Alejandra ; Beli, Petra ; Pellegrini, Luca ; Caldas, Carlos ; Deriano, Ludovic ; Jacobs, Jacqueline J L ; Galanty, Yaron ; Jackson, Stephen P

    Publisher

    England: Nature Publishing Group

    Journal title

    Nature cell biology, 2018, Vol.20 (8), p.954-965

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

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    English

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    Adenosine diphosphate Animals Biochemistry, Molecular Biology Bone Neoplasms - drug therapy Bone Neoplasms - genetics Bone Neoplasms - metabolism Bone Neoplasms - pathology BRCA1 protein BRCA1 Protein - deficiency BRCA1 Protein - genetics BRCA2 protein Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Cancer Cancer cells Care and treatment Cell Cycle Proteins Cell Line, Tumor Cellular Biology Cisplatin Cisplatin - pharmacology CRISPR Deactivation Deoxyribonucleic acid DNA DNA Breaks, Double-Stranded DNA damage DNA End-Joining Repair DNA-Binding Proteins Dose-Response Relationship, Drug Double-strand break repair Drug Resistance, Neoplasm - genetics Female Gene expression Genetic aspects Genetics Genomes HEK293 Cells Homologous recombination Homology Humans Inactivation Inhibitors Life Sciences Mad2 Proteins - genetics Mad2 Proteins - metabolism Mice Molecular biology Multiprotein Complexes Null cells Oligonucleotides Oligosaccharides Osteosarcoma - drug therapy Osteosarcoma - genetics Osteosarcoma - metabolism Osteosarcoma - pathology Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - metabolism Ovarian Neoplasms - pathology Poly(ADP-ribose) Poly(ADP-ribose) polymerase Poly(ADP-ribose) Polymerase Inhibitors - pharmacology Prostate Proteins Proteins - genetics Proteins - metabolism Recombinational DNA Repair Ribose Screens Single-stranded DNA Telomere-Binding Proteins - genetics Telomere-Binding Proteins - metabolism Tumor Suppressor p53-Binding Protein 1 - genetics Tumor Suppressor p53-Binding Protein 1 - metabolism Tumors Viability Xenograft Model Antitumor Assays

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6145444

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