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Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

Full title: Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

Author/creator: Gammage, Payam A, Viscomi, Carlo, Simard, Marie-Lune, Costa, Ana S H, Gaude, Edoardo, Powell, Christopher A, Van Haute, Lindsey, McCann, Beverly J, Rebelo-Guiomar, Pedro, Cerutti, Raffaele, Zhang, Lei, Rebar, Edward J, Zeviani, Massimo, Frezza, Christian, Stewart, James B, Minczuk, Michal.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

Language: English

Formats: Articles

Publishers: United States: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

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    Record title

    Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

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    Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

    Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

    Full title

    Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

    Author / Creator

    Gammage, Payam A ; Viscomi, Carlo ; Simard, Marie-Lune ; Costa, Ana S H ; Gaude, Edoardo ; Powell, Christopher A ; Van Haute, Lindsey ; McCann, Beverly J ; Rebelo-Guiomar, Pedro ; Cerutti, Raffaele ; Zhang, Lei ; Rebar, Edward J ; Zeviani, Massimo ; Frezza, Christian ; Stewart, James B ; Minczuk, Michal

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    United States: Nature Publishing Group

    Journal title

    Nature medicine, 2018, Vol.24 (11), p.1691-1695

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

    Language

    English

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    Articles

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    Analysis Animals Care and treatment Coronary artery disease Dependovirus - genetics Disease Models, Animal Disorders DNA binding proteins DNA, Mitochondrial - genetics Extrachromosomal DNA Gene Editing Gene mutations Genetic aspects Genetic diversity Genomes Genomics Health aspects Heart Heart diseases Heteroplasmy Humans Mice Mitochondria Mitochondria, Heart - genetics Mitochondria, Heart - pathology Mitochondrial diseases Mitochondrial Diseases - genetics Mitochondrial Diseases - pathology Mitochondrial Diseases - therapy Mitochondrial DNA Mutation Mutation - genetics Nuclease Nucleases Phenotypes Prognosis Reversion RNA, Transfer - genetics Viruses Zinc Zinc Finger Nucleases - genetics Zinc Finger Nucleases - therapeutic use

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6225988

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