SLNSW-EWS-FLI1 increases transcription to cause R-loops...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

Full title: EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

Author/creator: Gorthi, Aparna, Romero, July Carolina, Loranc, Eva, Cao, Lin, Lawrence, Liesl A, Goodale, Elicia, Iniguez, Amanda Balboni, Bernard, Xavier, Masamsetti, V Pragathi, Roston, Sydney, Lawlor, Elizabeth R, Toretsky, Jeffrey A, Stegmaier, Kimberly, Lessnick, Stephen L, Chen, Yidong, Bishop, Alexander J R.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

Language: English

Formats: Articles

Publishers: England: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

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    Record title

    EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

    Record identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

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    EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

    EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

    Full title

    EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

    Author / Creator

    Gorthi, Aparna ; Romero, July Carolina ; Loranc, Eva ; Cao, Lin ; Lawrence, Liesl A ; Goodale, Elicia ; Iniguez, Amanda Balboni ; Bernard, Xavier ; Masamsetti, V Pragathi ; Roston, Sydney ; Lawlor, Elizabeth R ; Toretsky, Jeffrey A ; Stegmaier, Kimberly ; Lessnick, Stephen L ; Chen, Yidong ; Bishop, Alexander J R

    Publisher

    England: Nature Publishing Group

    Journal title

    Nature (London), 2018, Vol.555 (7696), p.387-391

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

    Language

    English

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    Articles

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    Subjects and topics

    Bioinformatics Bone cancer BRCA1 protein BRCA1 Protein - antagonists & inhibitors BRCA1 Protein - metabolism Breast cancer Cancer Cell Line, Tumor Chemotherapy Damage accumulation Deoxyribonucleic acid DNA DNA Damage Etoposide Ewing's sarcoma Ewings sarcoma Experiments FLI-1 protein Fuses Gene expression Gene Expression Regulation, Neoplastic Gene regulation Genomes Genotoxic chemicals Genotoxicity Homologous recombination Homology Humans Insects Kinases Metabolism Nucleic Acid Conformation Oncogene Proteins, Fusion - genetics Oncogene Proteins, Fusion - metabolism Phosphorylation Poly(ADP-ribose) Polymerase 1 Proteins Proto-Oncogene Protein c-fli-1 - genetics Proto-Oncogene Protein c-fli-1 - metabolism R-loops Recombinational DNA Repair RNA polymerase RNA-Binding Protein EWS - genetics RNA-Binding Protein EWS - metabolism Sarcoma Sarcoma, Ewing - genetics Sarcoma, Ewing - metabolism Sensitivity Transcription Transcription, Genetic Translocation Tumors

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6318124

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