SLNSW-Second-generation IL-2 receptor-targeted diphther...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

Full title: Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

Author/creator: Cheung, Laurene S., Fu, Juan, Kumar, Pankaj, Kumar, Amit, Urbanowski, Michael E., Ihms, Elizabeth A., Parveen, Sadiya, Bullen, C. Korin, Patrick, Garrett J., Harrison, Robert, Murphy, John R., Pardoll, Drew M., Bishai, William R..

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

Language: English

Formats: Articles

Publishers: United States: National Academy of Sciences

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

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    Record title

    Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

    Record identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

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    Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

    Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

    Full title

    Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti–PD-1 in melanoma

    Author / Creator

    Cheung, Laurene S. ; Fu, Juan ; Kumar, Pankaj ; Kumar, Amit ; Urbanowski, Michael E. ; Ihms, Elizabeth A. ; Parveen, Sadiya ; Bullen, C. Korin ; Patrick, Garrett J. ; Harrison, Robert ; Murphy, John R. ; Pardoll, Drew M. ; Bishai, William R.

    Publisher

    United States: National Academy of Sciences

    Journal title

    Proceedings of the National Academy of Sciences - PNAS, 2019, Vol.116 (8), p.3100-3105

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

    Language

    English

    Formats

    Articles

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    Subjects and topics

    Agglomeration Amino acid substitution Amino Acid Substitution - genetics Antibodies Antibodies - administration & dosage Anticancer properties Antitumor activity Apoptosis Biological activity Biological Sciences Cancer cancer immunotherapy CD25 antigen Cell culture Cell death Cell Proliferation - drug effects Corynebacterium diphtheriae - chemistry Corynebacterium diphtheriae - pathogenicity Diphtheria Diphtheria Toxin - administration & dosage Diphtheria Toxin - chemistry Endothelial cells Fusion protein fusion toxin Human Umbilical Vein Endothelial Cells - drug effects Humans Immunogenicity Immunoregulation Immunosuppressive Agents - administration & dosage Immunotoxins - administration & dosage Inhibition Interleukin 2 Interleukin 2 receptors Interleukin-2 - administration & dosage Interleukin-2 - chemistry Interleukin-2 Receptor alpha Subunit - drug effects Lymphocytes Lymphocytes T Lymphoma Melanoma Melanoma, Experimental - drug therapy Melanoma, Experimental - genetics Melanoma, Experimental - immunology Melanoma, Experimental - pathology PD-1 protein Production methods Programmed Cell Death 1 Receptor - genetics Proteins Receptors, Interleukin-2 - genetics Receptors, Interleukin-2 - immunology Recombinant Fusion Proteins - administration & dosage Recombinant Fusion Proteins - chemistry T-cell lymphoma T-Lymphocytes, Regulatory - drug effects Toxicity Tregs Tumors Umbilical vein

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6386727

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