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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Full title: Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Author/creator: Kinsey, Conan G, Camolotto, Soledad A, Boespflug, Amelie M, Guillen, Katrin P, Foth, Mona, Truong, Amanda, Schuman, Sophia S, Shea, Jill E, Seipp, Michael T, Yap, Jeffrey T, Burrell, Lance D, Lum, David H, Whisenant, Jonathan R, Gilcrease, 3rd, G Weldon, Cavalieri, Courtney C, Rehbein, Kaitrin M, Cutler, Stephanie L, Affolter, Kajsa E, Welm, Alana L, Welm, Bryan E, Scaife, Courtney L, Snyder, Eric L, McMahon, Martin.

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Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

Language: English

Formats: Articles

Publishers: United States: Nature Publishing Group

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

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    Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

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    Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

    Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

    Full title

    Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

    Author / Creator

    Kinsey, Conan G ; Camolotto, Soledad A ; Boespflug, Amelie M ; Guillen, Katrin P ; Foth, Mona ; Truong, Amanda ; Schuman, Sophia S ; Shea, Jill E ; Seipp, Michael T ; Yap, Jeffrey T ; Burrell, Lance D ; Lum, David H ; Whisenant, Jonathan R ; Gilcrease, 3rd, G Weldon ; Cavalieri, Courtney C ; Rehbein, Kaitrin M ; Cutler, Stephanie L ; Affolter, Kajsa E ; Welm, Alana L ; Welm, Bryan E ; Scaife, Courtney L ; Snyder, Eric L ; McMahon, Martin

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    United States: Nature Publishing Group

    Journal title

    Nature medicine, 2019, Vol.25 (4), p.620-627

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

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    English

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    Articles

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    Adenocarcinoma Animals Autophagy Autophagy - drug effects CA-19-9 Antigen - metabolism Cancer Cancer cells Carcinogens Care and treatment Cell Line, Tumor Cellular signal transduction Chloroquine Chloroquine - pharmacology Colorectal carcinoma Cytotoxicity Drug therapy, Combination Extracellular signal-regulated kinase Genetic aspects Humans Hydroxychloroquine Inhibition Kinases LKB1 protein MAP Kinase Signaling System - drug effects Melanoma Mice, SCID Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinase Kinases - metabolism Pancreas Pancreatic cancer Pancreatic Neoplasms - enzymology Pancreatic Neoplasms - pathology Patients Phagocytosis Pharmacology Protein Kinase Inhibitors - pharmacology Proto-Oncogene Proteins B-raf - antagonists & inhibitors Proto-Oncogene Proteins B-raf - metabolism Pyridones - pharmacology Pyrimidinones - pharmacology Raf protein ras Proteins - metabolism Signal transduction Signaling Tumors Xenograft Model Antitumor Assays Xenografts Xenotransplantation

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    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

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    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6452642

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