SLNSW-Two PKA RIα holoenzyme states define ATP as an is...-TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP

Full title: Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP

Author/creator: Lu, Tsan-Wen, Wu, Jian, Aoto, Phillip C., Weng, Jui-Hung, Ahuja, Lalima G., Sun, Nicholas, Cheng, Cecilia Y., Zhang, Ping, Taylor, Susan S..

Call Numbers:

Record Identifier: TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

Language: English

Formats: Articles

Publishers: United States: National Academy of Sciences

Permalink: https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

Articles

Articles

Export this record

Export selected records

  • Export to excel
  • Permalink

    • Export record to excel

    File type to download

    Beta version

    Record title

    Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP

    Record identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

    Record permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

    Share

    Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP

    ACCESS
    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

    Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP

    Full title

    Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP

    Author / Creator

    Lu, Tsan-Wen ; Wu, Jian ; Aoto, Phillip C. ; Weng, Jui-Hung ; Ahuja, Lalima G. ; Sun, Nicholas ; Cheng, Cecilia Y. ; Zhang, Ping ; Taylor, Susan S.

    Publisher

    United States: National Academy of Sciences

    Journal title

    Proceedings of the National Academy of Sciences - PNAS, 2019, Vol.116 (33), p.16347-16356

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

    Language

    English

    Formats

    Articles

    Publication information

    Publisher

    Subjects

    Subjects and topics

    Activation Adenosine Triphosphate - chemistry Adenosine Triphosphate - genetics allosteric and orthosteric regulation Allosteric properties Allosteric Regulation - genetics Amino Acid Sequence - genetics ATP Biological Sciences cAMP Catalysis Crosstalk Crystallography, X-Ray Cyclic AMP Cyclic AMP - chemistry Cyclic AMP - genetics Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - chemistry Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - genetics Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - chemistry Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - genetics Cyclic AMP-Dependent Protein Kinases - chemistry Cyclic AMP-Dependent Protein Kinases - genetics Dimers Gene Expression Regulation, Enzymologic - genetics Holoenzymes - chemistry Holoenzymes - genetics Humans Interfaces isoform-specific quaternary structure Isoforms Kinases Magnesium PNAS Plus Protein Binding - genetics Protein kinase A Protein Structure, Quaternary Protein Subunits - chemistry Protein Subunits - genetics Signal Transduction - genetics structural biology Substrates

    More information

    — SCOPE AND CONTENTS

    Contents

    — ALTERNATIVE TITLES

    Full title

    — AUTHORS, ARTISTS AND CONTRIBUTORS

    Author / Creator

    Identifiers

    — PRIMARY IDENTIFIERS

    Record Identifier

    TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

    Permalink

    https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6697891

    — OTHER IDENTIFIERS

    ISSN

    E-ISSN

    DOI

    How to access this item

    Online

    1 item

    How to access?

    Login with a Library card

    Full text available >

    About resource >

    View in old catalogue

    Connecting people and collections