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CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

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Record title

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

Record identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707377

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

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https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707377

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

Full title

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

Publisher

England: Nature Publishing Group

Journal title

Nature (London), 2019, Vol.568 (7750), p.112-116

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707377

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

SCOPE AND CONTENTS

Contents

Chimeric antigen receptors (CARs) are synthetic antigen receptors that reprogram T cell specificity, function and persistence
. Patient-derived CAR T cells have demonstrated remarkable efficacy against a range of B-cell malignancies
, and the results of early clinical trials suggest activity in multiple myeloma
. Despite high complete resp...

ALTERNATIVE TITLES

Full title

CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707377

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6707377

OTHER IDENTIFIERS

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-1054-1

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