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Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

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Record title

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

Record identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810605

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

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https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810605

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

Full title

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2019, Vol.381 (4), p.317-327

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810605

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

SCOPE AND CONTENTS

Contents

Approximately 7% of pancreatic cancers occur in patients with a germline mutation in
BRCA1
or
BRCA2
, an alteration that compromises DNA repair. In a randomized trial in patients with metastatic pancreatic cancer that had responded to platinum-based chemotherapy, progression-free survival was nearly twice as long with olaparib than with...

ALTERNATIVE TITLES

Full title

Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer

Identifiers

PRIMARY IDENTIFIERS

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810605

Permalink

https://collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6810605

OTHER IDENTIFIERS

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1903387

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